PERSULFIDE PROPERTIES OF THIOCYSTINE AND RELATED TRISULFIDES
PERSULFIDE PROPERTIES OF THIOCYSTINE AND RELATED TRISULFIDES
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DOI：
10.1016/0045-2068(80)90026-7
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发表时间：
1980-01-01
影响因子：
5.1
通讯作者：
WOOD, JL
中科院分区：
文献类型：
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作者：
ABDOLRASULNIA, R;WOOD, JL
硫代半胱氨酸(双[2-氨基-2-羧乙基]三硫化物)作为过硫化物将其硫烷S转移到亲硫基上。这是通过形成活性中间体硫代半胱氨酸(丙氨酸二硫化氢)来实现的。在没有接受者的情况下，S以基本的形式被释放。硫代半胱氨酸在pH为2-9的范围内相对稳定。其转化为不稳定的硫代半胱氨酸的速度可被巯基化合物、锰试剂或能裂解S-S键以生成硫基的试剂加速。由于硫代半胱氨酸在生物[球形红假单胞菌]体系中被检测到，因此有人认为硫代半胱氨酸提供了一种硫烷的存储形式。与硫代半胱氨酸相关的三硫化物在性质上具有相似的性质。
Thiocystine (bis[2-amino-2-carboxyethyl]trisulfide) functions as a persulfide in transferring its sulfane S to thiophilic acceptors. This occurs by formation of a reactive intermediate, thiocysteine (alanine hydrogen disulfide). In the absence of an acceptor S is released in elemental form. Thiocystine is relatively stable in the pH range of 2-9. Its conversion to unstable thiocysteine is accelerated by sulfhydryl compounds, rhodanese, or reagents that cleave S-S bonds to yield sulfhydryl groups. Since thiocystine was detected in biological [Rhodopseudomonas sphaeroides] systems, it is proposed that it provides a storage form of sulfane S. Trisulfides related to thiocystine show qualitatively similar properties.