Oscillatory activity during maintenance of spatial and temporal information in working memory.
Oscillatory activity during maintenance of spatial and temporal information in working memory.
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DOI：
10.1016/j.neuropsychologia.2012.10.009
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发表时间：
2013-01
期刊：
影响因子：
2.6
通讯作者：
Ranganath C
中科院分区：
文献类型：
--
作者：
Roberts BM;Hsieh LT;Ranganath C
工作记忆（WM）过程有助于保持信息处于活跃状态，因此它可以用来指导未来的行为。虽然许多研究已经调查了人类和猴子与空间工作记忆相关的大脑活动，但很少有研究集中在工作记忆对时间顺序信息的神经机制上，以及时间和空间信息的处理如何不同。现有的证据表明，类似的额顶叶区域招募在时间和空间WM，虽然有数据表明，他们是不同的过程。允许这两种类型的信息的差异维护的机制尚不清楚。一种可能性是，神经振荡可能差异有助于时间和空间WM。在本研究中，我们使用头皮脑电图（EEG）比较模式的振荡活动在维护的空间和时间的信息在WM。EEG数据的时间-频率分析显示，与正确的空间试验相比，在正确的时间顺序试验的延迟期间，左额叶θ（5-8 Hz）增强，后α（9-12 Hz）增强，左后β（14-28 Hz）功率增强。与此相反，伽马（30-50赫兹）功率在右侧额叶网站增加在延迟期的空间WM试验，相比，时间WM试验。目前的结果是一致的想法，神经振荡模式提供了独特的机制，在WM的时间和空间信息的维护。具体来说，θ振荡是最关键的WM的时间信息的维护。更高频率的振荡在时间和空间记忆中的可能作用也进行了讨论。
Working Memory (WM) processes help keep information in an active state so it can be used to guide future behavior. Although numerous studies have investigated brain activity associated with spatial WM in humans and monkeys, little research has focused on the neural mechanisms of WM for temporal order information, and how processing of temporal and spatial information might differ. Available evidence indicates that similar frontoparietal regions are recruited during temporal and spatial WM, although there are data suggesting that they are distinct processes. The mechanisms that allow for differential maintenance of these two types of information are unclear. One possibility is that neural oscillations may differentially contribute to temporal and spatial WM. In the present study, we used scalp electroencephalography (EEG) to compare patterns of oscillatory activity during maintenance of spatial and temporal information in WM. Time-frequency analysis of EEG data revealed enhanced left frontal theta (5–8 Hz), enhanced posterior alpha (9–12 Hz), and enhanced left posterior beta (14–28 Hz) power during the delay period of correct temporal order trials compared to correct spatial trials. In contrast, gamma (30–50 Hz) power at right lateral frontal sites was increased during the delay period of spatial WM trials, as compared to temporal WM trials. The present results are consistent with the idea that neural oscillatory patterns provide distinct mechanisms for the maintenance of temporal and spatial information in WM. Specifically, theta oscillations are most critical for the maintenance of temporal information in WM. Possible roles of higher frequency oscillations in temporal and spatial memory are also discussed.
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DOI：
10.1073/pnas.1014528108
发表时间：
2011-06-28
影响因子：
11.1
作者：
Addante, Richard J.;Watrous, Andrew J.;Ranganath, Charan
通讯作者：
Ranganath, Charan
影响因子：
1.7
作者：
Delogu, Franco;Nijboer, Tanja C. W.;Postma, Albert
通讯作者：
Postma, Albert
影响因子：
56.9
作者：
FUSTER, JM;ALEXANDER, GE
通讯作者：
ALEXANDER, GE
影响因子：
16.2
作者：
Buschman, Timothy J.;Miller, Earl K.
通讯作者：
Miller, Earl K.
影响因子：
2.4
作者：
Gmeindl, Leon;Walsh, Megan;Courtney, Susan M.
通讯作者：
Courtney, Susan M.