A possible case of negative segregation distortion in the SD system of Drosophila melanogaster.
A possible case of negative segregation distortion in the SD system of Drosophila melanogaster.
复制标题
果蝇 SD 系统中负分离扭曲的可能情况。
DOI：
10.1093/genetics/121.2.263
复制
发表时间：
1989
期刊：
影响因子：
3.3
通讯作者：
Hiraizumi,Y
中科院分区：
文献类型：
--
作者：
Hiraizumi,Y
提出的模型来解释分离畸变果蝇的部分基础上的观察，在Sd杂合Rspi/Rsps男性，携带敏感的Rsps等位基因的染色体是扭曲的，但携带不敏感的Rspi等位基因的染色体不是。本研究的结果表明，情况可能并非总是如此。在一定的基因型条件下，携带Rsps等位基因的染色体可以以大于0.5（约0.6）的频率传递给后代，或者相应地，携带Rspi等位基因的染色体可能相对于具有Rsps等位基因的染色体发生畸变。因此，在男性中两个Rsp等位基因的相对敏感性和不敏感性不是绝对的，而是相对的;并且它们可以根据剩余基因型而颠倒。如果这是真的，一个重大的修改，目前的模式或一个全新的模式的建议可能成为必要的，以解释偏析扭曲令人满意的机制。
Models proposed to explain segregation distortion in Drosophila melanogaster are based partly upon the observation that, in the Sd heterozygous Rspi/Rsps male, the chromosome carrying the sensitive Rsps allele is distorted, but the chromosome carrying the insensitive Rspi allele is not. The results of the present study suggest that this may not always be the case. Under a certain genotypic condition, the chromosome carrying the Rsps allele can be transmitted to the progeny in frequencies of more than 0.5 (about 0.6), or correspondingly, the chromosome carrying the Rspi allele may be distorted with respect to the one with the Rsps allele. Thus, the relative sensitivity and insensitivity of the two Rsp alleles in a male are not absolute, but relative; and they may be reversed depending upon the residual genotype. If this is true, a major modification of the current models or a proposal of an entirely new model may become necessary to explain the mechanism of segregation distortion satisfactorily.