Corneal ulceration in South East Asia. II: A strategy for the prevention of fungal keratitis at the village level in Burma
Corneal ulceration in South East Asia. II: A strategy for the prevention of fungal keratitis at the village level in Burma
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DOI：
10.1136/bjo.2006.094706
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发表时间：
2006-08-01
影响因子：
4.1
通讯作者：
Whitcher, J. P.
中科院分区：
文献类型：
--
作者：
Maung, N.;Thant, C. C.;Whitcher, J. P.
目的：证明缅甸基层村卫生工作者(VHW)分发的局部抗真菌和抗生素预防措施是预防以真菌为主的溃疡人群创伤后微生物角膜炎的有效公共卫生干预措施。15名VHW前瞻性地跟踪了12个月，他们接受了培训，用荧光素染料和蓝色手电筒识别创伤后角膜擦伤，并对符合资格标准的人的眼睛每天三次使用1%氯霉素和1%克霉唑软膏。结果：在12个月期间，向VHW报告的273名眼外伤患者和126名VHW患者被发现有角膜擦伤。126例患者均使用1%氯霉素和1%克霉唑软膏，每日3次，连用3天，均痊愈，无后遗症。结论：在农村地区，只要采取相对简单的措施，就能有效地预防外伤性角膜擦伤后的真菌和细菌性溃疡，当地志愿公共卫生工作者很容易学会使用这些措施。
Aim: To prove that topical antifungal and antibiotic prophylaxis distributed by grass roots village health workers (VHWs) in Burma is an effective public health intervention for the prevention of post-traumatic microbial keratitis in a population where the majority of ulcers are fungal.Methods: Three villages in Bago District with a combined population of 16 987 were selected for the study. This defined population was followed prospectively for 12 months by 15 VHWs who were trained to identify post-traumatic corneal abrasions with fluorescein dye and a blue torch and to administer 1% chloramphenicol and 1% clotrimazole ointment three times a day for 3 days to the eyes of individuals who fulfilled the eligibility criteria.Results: During the 12 month period 273 individuals reported to VHWs with an ocular injury and 126 were found to have a corneal abrasion. All 126 were treated with 1% chloramphenicol and 1% clotrimazole ointment three times a day for 3 days, and all healed without sequelae.Conclusions: Both fungal and bacterial ulcers that occur following traumatic corneal abrasions can be effectively prevented in a village setting by using relatively simple measures that local volunteer public health workers can easily be taught to employ.