VASODILATION EVOKED FROM MEDULLA AND CEREBELLUM IS COUPLED TO BURSTS OF CORTICAL EEG ACTIVITY IN RATS
VASODILATION EVOKED FROM MEDULLA AND CEREBELLUM IS COUPLED TO BURSTS OF CORTICAL EEG ACTIVITY IN RATS
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DOI：
10.1152/ajpregu.1995.268.2.r454
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发表时间：
1995-02-01
影响因子：
2.8
通讯作者：
REIS, DJ
中科院分区：
文献类型：
--
作者：
GOLANOV, EV;REIS, DJ
在麻醉大鼠中，通过激光多普勒血流仪测量的脑血流量（rCBF）以类似于6次事件/min的速率自发波动。这些脑血管波（CW）之前是同时和同步爆发的皮质电活动类似于爆发抑制/纺锤波爆发脑电图模式。在小脑顶核或延髓头端腹外侧区的特定部位，单次电脉冲可诱发相同的爆发-CW复合波。这些包括，顺序，一个恒定的初始三相（正-负-正）电位反转极性在V层，可变后爆发，和短暂的rCBF升高出现类似于1.2秒后爆发发作。诱发爆发被出现的自发爆发所遮挡
Cerebral blood flow (rCBF), measured by laser-Doppler flowmetry, spontaneously fluctuates at similar to 6 events/min in the anesthetized rat. These cerebrovascular waves (CWs) are preceded by simultaneous and synchronous bursts of electrocorticographic activity similar to burst-suppression/spindle-burst electroencephalogram patterns. Identical burst-CW complexes are evoked by single electrical pulses of specific sites in the cerebellar fastigial nucleus or rostral ventrolateral medulla. These consist, sequentially, of a constant initial triphasic (positive-negative-positive) potential reversing polarity in lamina V, variable afterbursts, and transient elevations of rCBF appearing similar to 1.2 s after burst onset. Evoked bursts are occluded by spontaneous bursts appearing