STUDIES ON UREA CYCLE ENZYME LEVELS IN THE HUMAN FETAL LIVER AT DIFFERENT GESTATIONAL AGES
STUDIES ON UREA CYCLE ENZYME LEVELS IN THE HUMAN FETAL LIVER AT DIFFERENT GESTATIONAL AGES
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DOI：
10.1203/00006450-199202000-00010
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发表时间：
1992-02-01
影响因子：
3.6
通讯作者：
DEVI, BG
中科院分区：
文献类型：
--
作者：
BAIG, MMA;HABIBULLAH, CM;DEVI, BG
本文研究了57例男胎和49例女胎的肝组织中与氨解毒有关的尿素循环酶。18名男性和12名女性成年人的手术肝楔形活检作为对照。显着的酶活性被发现是本早在妊娠第13周。随着胎龄的增加，酶活性逐渐增加，在妊娠第36周达到成人活性的90%左右。
Urea cycle enzymes involved in the detoxification of ammonia were studied in liver tissues of 57 male and 49 female fetuses of different age groups ranging from 13 to 36 wk of gestation. Surgical wedge biopsies of liver from 18 male and 12 female adults were used as controls. Significant enzyme activity was found to be present as early as the 13th wk of gestation. As gestational age advanced, enzyme activity gradually increased, reaching about 90% of the adult activity by the 36th wk of gestation.