Anatomy based inverse planning in HDR prostate brachytherapy
Anatomy based inverse planning in HDR prostate brachytherapy
复制标题
DOI：
10.1016/j.radonc.2004.08.014
复制
发表时间：
2004-10-01
影响因子：
5.7
通讯作者：
Koper, PCM
中科院分区：
文献类型：
--
作者：
Kolkman-Deurloo, IKK;Deleye, XGJ;Koper, PCM
本研究的目的是评估柏拉图BPS 14.2中实施的基于解剖学的反向计划用于HDR前列腺植入物的计划。对6名患者进行了分析。采用几何优化后图形优化(GO)、基于解剖的逆规划或标准逆优化(SIO)、调谐逆优化(TO)和调谐逆优化后图优化(GOTO)的方法对剂量分布进行优化。GO、SiO、TiO和GOTiO的平均靶标覆盖率分别为93+/-4%、53+/-11%、74+/-8%、90+/-3%。GO、SiO和GOTiO的共形指数硬币分别为0.74+/-0.02、0.43+/-0.15和0.77+/-0.07。比较GOTiO和GO，发现剂量均匀度得到了改善。(C)2004爱思唯尔爱尔兰有限公司。保留所有权利。
The purpose of this study is to evaluate anatomy based inverse planning as implemented in PLATO BPS 14.2 for planning of HDR prostate implants. Six patients were analysed. The dose distributions were optimized using geometric optimization followed by graphical optimization (GO), anatomy based inverse planning or standard inverse optimization (SIO), tuned inverse optimization (TIO) and tuned inverse optimization followed by graphical optimization (GOTIO). The mean target coverage was 93 +/- 4%, 53 +/- 11%, 74 +/- 8%, 90 +/- 3%, respectively, for GO, SIO, TIO and GOTIO. The conformal index COIN was 0.74 +/- 0.02, 0.43 +/- 0.15 and 0.77 +/- 0.07, respectively, for GO, SIO and GOTIO. Improved dose homogeneity was found when comparing GOTIO with GO. (C) 2004 Elsevier Ireland Ltd. All rights reserved.