Evaluation of a matched filter resolution recovery reconstruction algorithm for SPECT-CT imaging

Evaluation of a matched filter resolution recovery reconstruction algorithm for SPECT-CT imaging
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DOI:
10.1097/mnm.0b013e32835ce5b5
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发表时间:
2013-03-01
影响因子:
1.5
通讯作者:
Murray, Iain
Murray, Iain
中科院分区:
医学4区
文献类型:
--
作者:
O'Mahoney, Eoin;Murray, Iain

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本研究的目的是评估在单光子发射计算机断层成像中应用Astonish分辨率恢复算法在空间分辨率和噪声控制方面的改进。次要目的是比较在这种情况下使用低能量通用准直器和使用低能量高分辨率准直器获得的图像,并评估更精细矩阵进一步提高图像质量的潜力。材料与方法采用tc -99m填充的热球Jaszczak模体来评估对比度和噪声。采用美国国家电气制造商协会的三线源单光子发射计算机断层扫描分辨率体来测量空间分辨率。使用低能量高分辨率和低能量通用准直器进行收购。结果与标准有序子集期望最大化重建相比,分辨率恢复算法获得了更高的空间分辨率(半最大时全宽度为8 mm比14 mm),从而减少了较小Jaszczak球体的部分体积效应。更高的图像对比度与较低的噪声水平同时实现。在分辨率恢复校正后的图像中观察到边缘增强伪影。对于较大的球体,也观察到对目标-背景活动的高估。结论该算法的使用使图像具有提高空间分辨率和降低噪声的特点。然而,2-3cm量级的小光源会明显过度增强。核医学杂志34:240-248 (C) 2013 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins。
Aim The aim of our study was to assess improvements in spatial resolution and noise control from the application of the Astonish resolution recovery algorithm for single photon emission computed tomography imaging. Secondary aims were to compare acquisitions made with low-energy general purpose collimators with those obtained using low-energy high-resolution collimators in this context and evaluate the potential of a finer matrix to improve image quality further.Materials and methods A Tc-99m-filled Jaszczak phantom with hot spheres was used to assess contrast and noise. A National Electrical Manufacturers Association triple line source single photon emission computed tomography resolution phantom was used to measure spatial resolution. Acquisitions were made using both low-energy high-resolution and low-energy general purpose collimators.Results Compared with standard ordered subsets expectation maximization reconstructions, the resolution recovery algorithm resulted in a higher spatial resolution (8 vs. 14 mm full-width at half-maximum) leading to reduced partial volume effects in the smaller Jaszczak spheres. Higher image contrast was achieved alongside lower levels of noise. An edge enhancement artefact was observed in the resolution recovery corrected images. An overestimate of the target-to-background activity was also observed for the larger spheres.Conclusion The use of such an algorithm results in images characterized by increased spatial resolution and reduced noise. However, small sources of the order of 2-3cm can be significantly overenhanced. Nucl Med Commun 34: 240-248 (C) 2013 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.