Highly flexible synthesis of indenylethylamines as ligand precursors for titanium complexes
Highly flexible synthesis of indenylethylamines as ligand precursors for titanium complexes
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DOI：
10.3998/ark.5550190.p008.859
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发表时间：
2015-01
期刊：
影响因子：
0.9
通讯作者：
J. Ross;Stefan H. Rohjans;M. Schmidtmann;S. Doye
中科院分区：
文献类型：
--
作者：
J. Ross;Stefan H. Rohjans;M. Schmidtmann;S. Doye
以2-（1-茚-1-基）乙醛为原料，与市售伯胺进行还原胺化反应，首次合成了各种茚基乙胺类化合物。此外，还提出了一种以廉价的茚和2-溴-1，1-二乙氧基乙烷为原料，两步合成2-（1H-茚-1-基）乙醛的新方法。最后，选择茚基乙胺作为配体前体用于合成相应的茚基乙基氨基钛络合物。后者的结果为相应的配合物作为重要化学反应的催化剂的应用铺平了道路。
Various indenylethylamines are synthesized for the first time by reductive amination of 2-(1Hinden-1-yl)acetaldehyde with commercially available primary amines. In addition, a new twostep synthesis of 2-(1H-inden-1-yl)acetaldehyde that uses inexpensive indene and 2-bromo-1,1diethoxyethane as starting materials is presented. Finally, a selected indenylethylamine is used as a ligand precursor for the synthesis of a corresponding indenylethylamido titanium complex. The latter result paves the way for applications of corresponding complexes as catalysts for important chemical reactions.