Epidemiology of osteoarthritis: Prevalence, risk factors and functional impact
Epidemiology of osteoarthritis: Prevalence, risk factors and functional impact
复制标题
DOI：
10.1007/bf03327356
复制
发表时间：
2003-10-01
影响因子：
4
通讯作者：
Rigon, C
中科院分区：
文献类型：
--
作者：
Corti, MC;Rigon, C
骨关节炎 (OA) 是最常见的关节炎形式，是导致老年人功能障碍和独立性降低的主要原因。髋部和膝部骨关节炎是社区成年人疼痛和身体残疾的两个最重要原因。有症状的手部骨关节炎是老年人的常见病，会损害手部功能，这种损害主要是由疼痛介导的。与其他慢性病一样，CA 的病因是多因素的，已经确定了一些局部和全身的危险因素。 CA 患病率的差异可能归因于遗传和生活方式因素。疾病定义可能基于临床或放射学标准，尽管病例定义应依赖于流行病学研究的放射学特征。本综述重点关注该疾病对功能的影响，描述患病率的地理差异，讨论疾病定义标准，并总结与 OA 风险相关的最常见风险因素，包括年龄。
Osteoarthritis (OA), the most common form of arthritis, is a major contributor to functional impairment and reduced independence in older adults. OA of the hip and knee are two of the most important causes of pain and physical disability in community-dwelling adults. Symptomatic hand OA is a common disease among the elderly, and impairs hand function, this impairment being largely mediated by pain. Like other chronic diseases, the etiology of CA is multifactorial, and several local and systemic risk factors have been identified. Differences in the prevalence of CA may be attributable to both genetic and life-style factors. Disease definition may be based upon clinical or radiographic criteria, although case definition should rely an radiographic features for epidemiological studies. This review focuses on the functional impact of the disease, describes geographic differences in prevalence rates, discusses disease definition criteria, and summarizes the most common risk factors, including age, associated with the risk of OA.