Human salivary alpha-amylase reactivity in a psychosocial stress paradigm
Human salivary alpha-amylase reactivity in a psychosocial stress paradigm
复制标题
DOI：
10.1016/j.ijpsycho.2004.09.009
复制
发表时间：
2005-03-01
影响因子：
3
通讯作者：
Ehlert, U
中科院分区：
文献类型：
--
作者：
Nater, UM;Rohleder, N;Ehlert, U
应激反应的生物学指标在心理生理学研究和临床实践中是有价值的标志物。由于据报道唾液酶α-淀粉酶的释放对生理和心理应激源作出反应，我们开始采用可靠的实验室应激方案来研究人唾液α-淀粉酶的变化，以研究唾液α-淀粉酶对短暂的心理社会应激的反应性。24名健康成人按随机顺序在不同日期暴露于TSST和对照条件。心理社会应激组与安静组相比，α-淀粉酶活性[F（3.74，86.06）=4.52; P=0.003]、皮质醇水平[F（4.21，88.32）-12.48; P
Biological indicators for stress reactions are valuable markers in psychophysiological research and clinical practice. Since the release of salivary enzyme alpha-amylase was reported to react to physiological and psychological stressors, we set out to investigate human salivary alpha-amylase changes employing a reliable laboratory stress protocol to investigate the reactivity of salivary alpha-amylase to a brief period of psychosocial stress.In a within-subject repeated-measures design, 24 healthy adults were exposed to the TSST and a control condition on separate days with randomized sequence. Salivary alpha-amylase, salivary cortisol and heart rate were repeatedly measured before, during and after both conditions.Significant differences between psychosocial stress and the rest condition in alpha-amylase activity [F(3.74,86.06)=4.52; P=0.003], cortisol levels [F(4.21,88.32)-12.48; P