Auditory cues can modify the gait of persons with early-stage Parkinson's disease:: a method for enhancing parkinsonian walking performance?
Auditory cues can modify the gait of persons with early-stage Parkinson's disease:: a method for enhancing parkinsonian walking performance?
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DOI：
10.1191/0269215503cr621oa
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发表时间：
2003-07-01
影响因子：
3
通讯作者：
Oldham, JA
中科院分区：
文献类型：
--
作者：
Howe, TE;Lövgreen, B;Oldham, JA
目的：为了研究是否系统地调整听觉线索的速率诱导早期帕金森病患者步态的时间和空间参数的相应调制。设计：受试者在无线索和四种线索条件下沿水平地板沿着行走15个9米;线索条件的顺序是随机的。11例早期特发性帕金森病受试者干预措施：从最初的三次无提示步行中建立首选的步伐。对每个受试者在随后的步行过程中提供的听觉线索的速率进行了系统的调整，分别代表他们在首选步行步速下平均步频的85%、92.5%、107.5%和115%。主要结果测量：平均步频、平均步长和平均速度。重复测量方差分析表明，受试者步态的平均速度和平均步频显著（p小于或等于0.01）相对于基线值在提示率为115和107.5%时增加，在提示率为85%时减少。平均步长是不受影响的线索率的变化。结论：率的听觉线索，在测试范围内，可以调制节奏，从而与早期帕金森氏病的受试者的步态速度。听觉提示的提供提供了一个潜在的策略，以提高这些患者的行走性能。
Objective: To investigate whether systematically adjusting the rate of auditory cues induces corresponding modulations of the temporal and spatial parameters of gait of patients with early-stage Parkinson's disease.Design: Subjects performed a series of 15 9-metre walks along a level floor under uncued and four cued conditions; the order of cued conditions was randomized.Setting: A physiotherapy gymnasium, Manchester, UK.Subjects: Eleven subjects with early-stage idiopathic Parkinson's disease.Interventions: Preferred pace was established from the initial three uncued walks. The rate of auditory cues delivered throughout subsequent walks was systematically adjusted for each subject, representing 85, 92.5, 107.5 and 115% of their mean cadence at preferred walking pace.Main outcome measures: Mean cadence, mean stride length and mean velocity.Results: Repeated measures ANOVA indicated that the mean velocity and mean cadence of subjects' gait significantly (p less than or equal to 0.01) increased relative to baseline values at cue rates of 115 and 107.5% of cadence at preferred pace and decreased at cue rate of 85%. Mean stride length was unaffected by variations in cue rate.Conclusion: The rate of auditory cues, within the range tested, can modulate cadence and thus velocity of gait of subjects with early-stage Parkinson's disease. The provision of auditory cues provides a potential strategy for enhancing walking performance in these patients.