The complexity of string partitioning

The complexity of string partitioning
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字符串分区的复杂性

DOI:
10.1007/978-3-642-31265-6_13
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发表时间:
2012
期刊:
Theor. Comput. Sci.
影响因子:
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通讯作者:
Chris Thachuk
Chris Thachuk
中科院分区:
--
文献类型:
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作者:
A. Condon;Ján Manuch;Chris Thachuk

文献摘要

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相似文献

给定一个有限字母表Σ上的字符串w和一个整数K,是否可以将w分割成至多K个长度的字符串,使得没有冲突?我们将这个问题称为字符串划分问题,并证明了对于碰撞的各种定义和一些有趣的限制,包括|Σ|=2,它是NP完全的。这确立了当代合成生物学中的一个重要问题的难度,即用于基因合成的寡聚设计。
Given a string w over a finite alphabet Σ and an integer K, can w be partitioned into strings of length at most K, such that there are no collisions? We refer to this question as the string partition problem and show it is NP-complete for various definitions of collision and for a number of interesting restrictions including |Σ|=2. This establishes the hardness of an important problem in contemporary synthetic biology, namely, oligo design for gene synthesis.