SPDB: a specialized database and web-based analysis platform for swine pathogens
SPDB: a specialized database and web-based analysis platform for swine pathogens
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SPDB：猪病原体专业数据库和网络分析平台
DOI：
10.1093/database/baaa063
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发表时间：
2020-08-06
影响因子：
5.8
通讯作者：
Yan, He
中科院分区：
文献类型：
--
作者：
Wang, Xiaoru;Liu, Zongbao;Yan, He
摘要快速、准确地诊断猪病是减少其对养猪业的负面影响所必不可少的。下一代测序技术是一种很有前途的猪病诊断工具。为了支持NGS在猪病诊断中的应用，我们建立了猪病病原体数据库（SPDB）。SPDB是第一个全面和高度专业化的猪病原体数据库和分析平台。目前的版本具有在线基因组搜索工具，现在包含26148个猪，猪病原体和猪遗传学相关物种的基因组。该数据库基于靶向16S rRNA基因测序和宏基因组NGS数据，为临床样本中4403种猪病原体及其相关物种的鉴定提供了全面的生物信息学分析管道。SPDB为兽医和研究人员提供强大且用户友好的服务，以支持NGS在猪病研究中的应用。数据库URL：http://spdatabase.com:2080/
Abstract The rapid and accurate diagnosis of swine diseases is indispensable for reducing their negative impacts on the pork industry. Next-generation sequencing (NGS) is a promising diagnostic tool for swine diseases. To support the application of NGS in the diagnosis of swine disease, we established the Swine Pathogen Database (SPDB). The SPDB represents the first comprehensive and highly specialized database and analysis platform for swine pathogens. The current version features an online genome search tool, which now contains 26 148 genomes of swine, swine pathogens and phylogenetically related species. This database offers a comprehensive bioinformatics analysis pipeline for the identification of 4403 swine pathogens and their related species in clinical samples, based on targeted 16S rRNA gene sequencing and metagenomic NGS data. The SPDB provides a powerful and user-friendly service for veterinarians and researchers to support the applications of NGS in swine disease research. Database URL: http://spdatabase.com:2080/