Adaptive bone remodeling around bonded noncemented total hip arthroplasty: a comparison between animal experiments and computer simulation.
Adaptive bone remodeling around bonded noncemented total hip arthroplasty: a comparison between animal experiments and computer simulation.
复制标题
围绕粘合非骨水泥全髋关节置换术的适应性骨重塑：动物实验与计算机模拟之间的比较。
DOI：
10.1002/jor.1100110405
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Galante,JO
中科院分区：
文献类型：
--
作者：
Weinans,H;Huiskes,R;vanRietbergen,B;Sumner,DR;Turner,TM;Galante,JO
与应力遮挡相关的严重骨丢失是威胁非骨水泥型全髋关节置换术长期完整性的一个问题。普遍认为这种现象是由根据Wolff定律的适应性骨重建引起的。最近，定量骨重建理论已被提出，适用于结合有限元代码的计算机模拟模型，可用于模拟重建过程的长期影响。在本文中，这样的计算机模拟的结果进行了比较，在动物实验。根据关于在犬中植入全涂层股骨髋关节假体的动物实验配置构建三维有限元模型。将自适应骨重塑过程的模拟结果（骨膜表面的几何适应和松质骨内的密度适应）与2年随访后犬股骨的横截面测量结果进行比较。详细的比较表明，全髋关节置换术股骨部件周围骨形态的长期变化可以用目前的定量自适应骨重建理论完全解释。
Severe loss of bone related to stress‐shielding is one problem threatening the long‐term integrity of noncemented total hip arthroplasty. It is widely accepted that this phenomenon is caused by adaptive bone remodeling according to Wolff's law. Recently, quantitative bone‐remodeling theories have been proposed, suitable for use in computer‐simulation models in combination with finite‐element codes, which can be applied to simulate the long‐term effect of the remodeling process. In the present paper, the results of such a computer simulation are compared with those in an animal experiment. A three‐dimensional finite‐element model was constructed from an animal experimental configuration concerning the implantation of a fully coated femoral hip prosthesis in dogs. The simulation results of the adaptive bone‐remodeling process (geometric adaptations at the periosteal surface and density adaptations within the cancellous bone) were compared with cross‐sectional measurements of the canine femurs after 2 years of follow‐up. The detailed comparison showed that long‐term changes in the morphology of bone around femoral components of total hip replacements can be fully explained with the present quantitative adaptive bone‐remodeling theory.