Improved radial GRAPPA calibration for real-time free-breathing cardiac imaging.
Improved radial GRAPPA calibration for real-time free-breathing cardiac imaging.
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DOI：
10.1002/mrm.22618
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发表时间：
2011-02
影响因子：
3.3
通讯作者：
Griswold, Mark
中科院分区：
文献类型：
--
作者：
Seiberlich, Nicole;Ehses, Philipp;Duerk, Jeff;Gilkeson, Robert;Griswold, Mark
为了生成实时的、非门控的、自由呼吸的心脏图像，欠采样的径向轨迹结合径向GRAPPA形式的并行成像已经显示出希望。然而，由于为校准GRAPPA权重集而必须作出的假设，这种方法在高欠采样系数下开始失效。本文针对实时心脏成像所需的高加速因子，提出了一种新颖的径向GRAPPA校正方法，大大提高了图像质量。这种全程校准方法提供了比标准径向GRAPPA更好的图像质量，但它需要获取许多额外的校准帧。将本文提出的贯通时间定标方法与标准的贯通k空间径向GRAPPA定标方法相结合，可以用较少的定标帧重建具有高加速因子的图像。研究了穿透时间和混合穿透时间/穿透k空间方法，以确定R=6活体短轴心脏图像的最有利校准参数。一旦建立了校准参数，然后将它们用于重建几个时间分辨率优于45ms的在体实时自由呼吸心脏数据集，其中一个的时间分辨率为35ms，平面内分辨率为1.56mm2。
In order to generate real-time, non-gated, free-breathing cardiac images, the undersampled radial trajectory combined with parallel imaging in the form of radial GRAPPA has shown promise. However, this method starts to fail at high undersampling factors due to the assumptions that must be made for the purposes of calibrating the GRAPPA weight sets. In this manuscript, a novel through-time radial GRAPPA calibration scheme is proposed which greatly improves image quality for the high acceleration factors required for real-time cardiac imaging. This through-time calibration method offers better image quality than standard radial GRAPPA, but it requires many additional calibration frames to be acquired. By combining the through-time calibration method proposed here with the standard through-k-space radial GRAPPA calibration method, images with high acceleration factors can be reconstructed using few calibration frames. Both the through-time and the hybrid through-time/through-k-space methods are investigated to determine the most advantageous calibration parameters for an R=6 in vivo short-axis cardiac image. Once the calibration parameters have been established, they are then used to reconstruct several in vivo real-time, free-breathing cardiac datasets with temporal resolutions better than 45ms, including one with a temporal resolution of 35ms and an in-plane resolution of 1.56mm2.
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