Relationship between Longitudinal Strain and Symptomatic Status in Aortic Stenosis
Relationship between Longitudinal Strain and Symptomatic Status in Aortic Stenosis
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DOI：
10.1016/j.echo.2013.05.004
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发表时间：
2013-08-01
影响因子：
6.5
通讯作者：
Messika-Zeitoun, David
中科院分区：
文献类型：
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作者：
Attias, David;Macron, Laurent;Messika-Zeitoun, David
背景资料：使用二维斑点追踪成像评估的整体纵向应变（GLS）和基础纵向应变（BLS）已被提议作为左心室（LV）收缩功能障碍的微妙标志物，对主动脉瓣狭窄（AS）患者具有潜在的预后价值。本研究的目的是评估纵向应变和症状状态之间的关系与AS。方法：GLS和BLS测量171例纯粹的，孤立的，至少轻度AS前瞻性地在两个机构招募。人群被分为四组：无症状的非重度AS（n = 55），无症状的重度AS伴左室射血分数（LVEF; >= 50%）（n = 37），有症状的重度AS伴LVEF（n = 60），重度AS伴LVEF（
Background: Global longitudinal strain (GLS) and basal longitudinal strain (BLS) assessed using two-dimensional speckle-tracking imaging have been proposed as subtle markers of left ventricular (LV) systolic dysfunction with potential prognostic value in patients with aortic stenosis (AS). The aim of this study was to evaluate the relationship between longitudinal strain and symptomatic status in patients with AS.Methods: GLS and BLS were measured in 171 patients with pure, isolated, at least mild AS prospectively enrolled at two institutions. The population was divided into four groups: asymptomatic nonsevere AS (n = 55), asymptomatic severe AS with preserved LV ejection fraction (LVEF; >= 50%) (n = 37), symptomatic severe AS with preserved LVEF (n = 60), and severe AS with reduced LVEF (