Similar prediction of total mortality, diabetes incidence and cardiovascular events using relative-and absolute-component Mediterranean diet score: The SUN cohort
Similar prediction of total mortality, diabetes incidence and cardiovascular events using relative-and absolute-component Mediterranean diet score: The SUN cohort
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DOI：
10.1016/j.numecd.2011.10.009
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发表时间：
2013-05-01
影响因子：
3.9
通讯作者：
Martinez-Gonzalez, M. A.
中科院分区：
文献类型：
--
作者：
Dominguez, L. J.;Bes-Rastrollo, M.;Martinez-Gonzalez, M. A.
背景和目的：积累的证据支持地中海式饮食（MeDiet）在降低死亡率和预防多种慢性疾病方面的有效性。广泛使用的分数来评估对 MeDiet 的依从性是基于特定的样本特征；或者，它们可以根据特定食物组消费的绝对/规范截止点（预先定义的份量/天或/周）来构建。本研究的目的是比较样本特定的 MeDiet 依从性评分 (MDS) 与绝对规范评分 (Mediterranean Diet Adherence Screener e MEDAS) 与常量营养素摄入量、总死亡率和慢性病发病率的关系。设计：SUN (Seguimiento Universidad de Navarra) 动态前瞻性队列研究（60.5% 为女性；平均年龄 38.4 岁）。 方法和结果：在横断面分析 (n=20,155) 中，我们根据 MDS（基于 136 项 FFQ）、MEDAS（基于 13 个问题）以及两者的变体评估常量营养素的分布。在前瞻性分析（n=9109；平均随访：6.2 年）中，我们评估了疾病发生率或死亡率。对 MeDiet 的坚持随着年龄的增长而增加，并且正如预期的那样，根据所有分数，与较高的纤维摄入量、较低的总脂肪摄入量以及较高的单不饱和/饱和脂肪比率相关。在最初没有癌症、糖尿病和心血管疾病 (CVD) 的受试者中，与基于 136 项 FFQ (MDS) 的样本特定评分相比，使用绝对规范评分 (MEDAS) 评估的 MeDiet 坚持率同样可以预测宏量营养素分布和疾病发病率或死亡率（糖尿病发病率、CVD 或全因死亡率）。 结论：坚持 MeDiet 与综合结果的发生率降低相关，包括糖尿病发病率、心血管事件发生率或全因死亡率。 (C) 2011 Elsevier B.V. 保留所有权利。
Background and Aim: Accumulated evidence supports the effectiveness of Mediterranean-type diets (MeDiet) in reducing mortality and preventing several chronic diseases. Widely used scores to assess adherence to MeDiet are based on specific sample characteristics; alternatively, they might be built according to absolute/normative cut-off points for the consumption of specific food groups (pre-defined servings/dayor/week). The aim of this study was to compare sample-specific MeDiet adherence scores (MDS) versus absolutenormative scores (Mediterranean Diet Adherence Screener e MEDAS) on their association with macronutrient intake, total mortality and incidence of chronic diseases. Design: SUN (Seguimiento Universidad de Navarra) dynamic prospective cohort study (60.5% women; mean age 38.4 years).Methods and Results: In cross-sectional analyses (n=20,155) we evaluated macronutrient distribution according to MDS (based on 136-item FFQ), MEDAS (based on 13 questions), and variants of both. In prospective analyses (n=9109; mean follow-up: 6.2 years), we evaluated disease incidence or mortality. Adherence to MeDiet increased with age and, as expected, was associated with higher fiber intake, lower total fat intake but higher monounsaturated/ saturated fat ratio, using all scores. Among subjects initially free of cancer, diabetes, and cardiovascular disease (CVD), adherence to MeDiet appraised with an absolute-normative score (MEDAS) similarly predicted macronutrient distribution and disease incidence or mortality diabetes incidence, CVD or all-cause mortality), when compared to a sample-specific score based on 136-item FFQ (MDS).Conclusions: Adherence to MeDiet was associated with a decreased incidence of a composite outcome including diabetes incidence, cardiovascular events incidence or all-cause mortality. (C) 2011 Elsevier B.V. All rights reserved.