Development of classification criteria for discoid lupus erythematosus: Results of a Delphi exercise
Development of classification criteria for discoid lupus erythematosus: Results of a Delphi exercise
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DOI：
10.1016/j.jaad.2017.02.030
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发表时间：
2017-08-01
影响因子：
13.8
通讯作者：
Merola, Joseph F.
中科院分区：
文献类型：
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作者：
Elman, Scott A.;Joyce, Cara;Merola, Joseph F.
背景：目前盘状红斑狼疮 (DLE) 尚无分类标准，这导致观察性和介入性研究工作中存在异质性问题。目标：我们寻求根据该领域相关利益相关者的国际专家意见共识来制定 DLE 分类标准。方法：使用德尔菲共识流程和名义组技术，生成分类标准的潜在项目。专家们根据项目的适当性和区分 DLE 与其他诊断的能力对项目进行排名，随后通过共识练习将项目删除。结果：生成了 12 个临床和组织病理学项目的最终列表，以便通过正式的持续验证过程可能纳入一组 DLE 分类标准。局限性：参与者主要由北美和欧洲的 DLE 专家组成。结论：这项工作代表了制定正式 DLE 分类标准的关键一步。
Background: No classification criteria currently exist for discoid lupus erythematosus (DLE), which has led to problematic heterogeneity in both observational and interventional research efforts.Objectives: We sought to develop DLE classification criteria based on consensus of international expert opinion of relevant stakeholders in the field.Methods: Using a Delphi consensus process and nominal group techniques, potential items for classification criteria were generated. Experts ranked items in terms of their appropriateness and ability to discriminate DLE from other diagnoses, and items were subsequently eliminated using consensus exercises.Results: A final list of 12 clinical and histopathologic items was generated for potential inclusion into a set of DLE classification criteria through a formal ongoing validation process.Limitations: The participants are predominantly composed of DLE experts in North America and Europe.Conclusion: This work represents a key step toward the development of formal DLE classification criteria.