LV mass assessed by echocardiography and CMR, cardiovascular outcomes, and medical practice.
LV mass assessed by echocardiography and CMR, cardiovascular outcomes, and medical practice.
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DOI：
10.1016/j.jcmg.2012.06.003
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发表时间：
2012-08
影响因子：
14
通讯作者：
Lima, Joao A. C.
中科院分区：
文献类型：
--
作者：
Armstrong, Anderson C.;Gidding, Samuel;Gjesdal, Ola;Wu, Colin;Bluemke, David A.;Lima, Joao A. C.
我们研究了与左心室质量（LVM）临床应用相关的三个重要领域：超声心动图和心脏磁共振（CMR）评估的准确性，预测心血管结局的能力，以及不同索引方法的比较价值。超声心动图估计左心室质量的推荐公式使用线性测量值，并基于左心室为旋转长椭球体的假设。CMR允许对左心室进行建模，而无需心脏几何假设或声学窗口依赖性，显示出更好的准确性和再现性。然而，超声心动图具有较低的成本，更容易获得，更好的耐受性。从Medline数据库中，确定了26项纵向超声心动图研究和5项CMR研究，研究了左心室质量或左心室肥大作为死亡或主要心血管结局的预测因素。使用这两种模式，左心室质量和左心室肥大是可靠的心血管风险预测因子。然而，没有研究直接比较方法预测事件的能力、肥大分类的一致性或心血管风险重新分类的性能。最早使用的标准化方法是将左心室质量指数转换为体表面积指数，但这似乎低估了肥胖和超重受试者的肥大患病率。从临床和科学的角度来看，将身高除以1.7或2.7作为异速生长幂是最有前途的标准化方法，用于将心肌质量按体重缩放。科学协会应通过各种测量技术对左心室质量的测量、左心室质量指数的计算和左心室肥厚的分类进行标准化，并由临床医生在风险分层和治疗决策中采用。
We investigate three important areas related to the clinical use of LVM (LVM): accuracy of assessments by echocardiography and cardiac magnetic resonance (CMR), the ability to predict cardiovascular outcomes, and the comparative value of different indexing methods. The recommended formula for echocardiographic estimation of LVM uses linear measurements and is based on the assumption of the left ventricle as a prolate ellipsoid of revolution. CMR permits a modeling of the left ventricle free of cardiac geometric assumptions or acoustic window dependency, showing better accuracy and reproducibility. However, echocardiography has lower cost, easier availability, and better tolerability. From the Medline database, 26 longitudinal echocardiographic studies and 5 CMR studies, investigating LVM or LV hypertrophy as predictors of death or major cardiovascular outcomes, were identified. LVM and LV hypertrophy were reliable cardiovascular risk predictors using both modalities. However, no study directly compared the methods for the ability to predict events, agreement in hypertrophy classification, or performance in cardiovascular risk reclassification. Indexing LVM to BSA was the earliest normalization process used, but it seems to underestimate the prevalence of hypertrophy in obese and overweight subjects. Dividing LVM by height to 1.7 or 2.7 as allometric powers are the most promising normalization methods in terms of practicality and usefulness from a clinical ans scientific standpoints for scaling myocardial mass to body size. The measurement of LVM, calculation of LVMi, and classification for LVH should be standardized by scientific societies across measurement techniques and adopted by clinicians in risk stratification and therapeutic decision.
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影响因子：
37.8
作者：
Dewey, Frederick E.;Rosenthal, David;Ashley, Euan A.
通讯作者：
Ashley, Euan A.
影响因子：
3.3
作者：
Alfakih, K;Bloomer, T;Sivananthan, M
通讯作者：
Sivananthan, M
影响因子：
2.7
作者：
Cuspidi, C.;Meani, S.;Mancia, G.
通讯作者：
Mancia, G.
影响因子：
3.2
作者：
de Simone, G;Devereux, RB;Verdecchia, P
通讯作者：
Verdecchia, P
影响因子：
3.2
作者：
Cuspidi, Cesare;Esposito, Arturo;Mancia, Giuseppe
通讯作者：
Mancia, Giuseppe