Lower endoscopy and prevention of colon cancer.
Lower endoscopy and prevention of colon cancer.
复制标题
下消化道镜检查与结肠癌的预防。
DOI：
10.1053/j.gastro.2014.05.019
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发表时间：
2014
期刊：
影响因子：
29.4
通讯作者：
Gupta,Samir
中科院分区：
文献类型：
--
作者：
Boland,BrigidS;Rivera-Nieves,Jesús;Gupta,Samir
Colonoscopy is widely recommended for early detection and prevention of colorectal cancer (CRC) based on obser-vational and modeling studies (Gastroenterology 2008; 149: 627–637). However, the impact of colonoscopy on CRC incidence and mortality (particularly in the right colon), as well as its potential added benfit over other tests, such as sigmoidoscopy, are uncertain (Ann Intern Med 2011; 154: 22–30).Nishihara et al used prospectively collected data from 2 large, well–characterized cohorts (the Nurses’ Health Study and the Health Professional Follow-up Study), to study outcomes of exposure to lower endoscopy. The primary outcomes were CRC incidence, CRC mortality, and molecular characteristics of post colonoscopy CRCs. The primary exposures were sigmoidoscopy, colonoscopy, and colonos-copy with polypectomy as reported on biennial patient questionnaires.
