Spindle frequency remains slow in sleep apnea patients throughout the night
Spindle frequency remains slow in sleep apnea patients throughout the night
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DOI：
10.1016/s1389-9457(03)00155-2
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发表时间：
2003-07-01
期刊：
影响因子：
4.8
通讯作者：
Hasan, J
中科院分区：
文献类型：
--
作者：
Himanen, SL;Virkkala, J;Hasan, J
背景资料：我们之前的数据表明，在正常睡眠中，个体睡眠纺锤波的频率与睡眠深度有关，可能与睡眠压力有关。到目前为止，睡眠障碍患者的纺锤波频率模式还没有研究。预计纺锤波频率可能会受到睡眠片段干扰sleep process.Methods：12例呼吸暂停患者与年龄和性别匹配的对照组进行了研究，与整夜睡眠记录。睡眠纺锤波的视觉选择和他们的频率被确定的频谱analysis.Results：睡眠纺锤波的患者一般慢于对照组。在我们以前的研究中，在非快速眼动（NREM）睡眠发作的中间部分的纺锤体的频率增加到晚上结束时，在对照组，而在患者组没有这样的增加被发现。结论：在呼吸暂停患者的慢纺锤体频率可以表明睡眠紊乱和改变的神经机制的结构调节睡眠纺锤体活动。(C)2003 Elsevier Science B.V.保留所有权利。
Background: Our previous data suggested that in normal sleep the frequency of individual sleep spindles would be related to sleep depth and possibly to sleep pressure. Thus far spindle frequency patterns in patients with sleep disorders have not been studied. It would be expected that the spindle frequencies might be affected by sleep fragmentation disturbing the sleep process.Methods: Twelve apnea patients with age- and sex-matched control subjects were studied with whole-night sleep recordings. Sleep spindles were visually selected and their frequency was determined by spectral analysis.Results: Sleep spindles of the patients were in general slower than in the control subjects. As in our previous study, the frequency of the spindles in the middle-part of the non-rapid eye movement (NREM) sleep episodes increased towards the end of the night in the control group, whereas in the patient group no such increase was found.Conclusions: The slow spindle frequencies in apnea patients could indicate disturbed sleep and altered neural mechanisms in the structures regulating sleep spindle activity. (C) 2003 Elsevier Science B.V. All rights reserved.