Force characteristics of the rat sternomastoid muscle reinnervated with end-to-end nerve repair.
Force characteristics of the rat sternomastoid muscle reinnervated with end-to-end nerve repair.
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DOI：
10.1155/2011/173471
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发表时间：
2011
影响因子：
--
通讯作者：
Mu L
中科院分区：
文献类型：
--
作者：
Sobotka S;Mu L
本研究的目的是建立与神经端端吻合（EEA），这可以作为一个基线，用于评估新的神经再支配技术的疗效后，大鼠胸锁乳突肌（SM）肌肉的力数据。切断一侧SM肌的神经使其麻痹，然后在不同的时间点进行EEA：即刻EEA，1个月和3个月延迟EEA。在3个月的恢复期结束时，通过测量肌肉力量并与对侧对照肌肉的力量进行比较来评估再神经支配的SM肌肉的功能恢复的程度。我们的研究结果表明，立即再神经SM产生约60%的最大强直性肌力的控制。延迟神经修复的SM产生约40%的最大力。EEA后肌力恢复不佳证明了开发替代手术技术治疗肌肉麻痹的重要性。
The goal of this study was to establish force data for the rat sternomastoid (SM) muscle after reinnervation with nerve end-to-end anastomosis (EEA), which could be used as a baseline for evaluating the efficacy of new reinnervation techniques. The SM muscle on one side was paralyzed by transecting its nerve and then EEA was performed at different time points: immediate EEA, 1-month and 3-month delay EEA. At the end of 3-month recovery period, the magnitude of functional recovery of the reinnervated SM muscle was evaluated by measuring muscle force and comparing with the force of the contralateral control muscle. Our results demonstrated that the immediately reinnervated SM produced approximately 60% of the maximal tetanic force of the control. The SM with delayed nerve repair yielded approximately 40% of the maximal force. Suboptimal recovery of muscle force after EEA demonstrates the importance of developing alternative surgical techniques to treat muscle paralysis.