Radical additions of xanthates to vinyl epoxides and related derivatives: A powerful tool for the modular creation of quaternary centers
Radical additions of xanthates to vinyl epoxides and related derivatives: A powerful tool for the modular creation of quaternary centers
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DOI：
10.1002/anie.200601567
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发表时间：
2006-01-01
影响因子：
16.6
通讯作者：
Zard, Samir Z.
中科院分区：
文献类型：
--
作者：
Charrier, Nicolas;Gravestock, David;Zard, Samir Z.
一个开放关系：三乙基硼烷/ o2介导的黄药加成到环氧乙烯及其衍生物代表了形成碳-碳键的有效过程。在温和的条件下，使用现成的试剂（见方案，Bn =苄基），可以以模块化、收敛的方式快速组装复杂结构。事实证明，四元中心的形成特别容易。©2006 Wiley-VCH Verlag GmbH & Co. KGaA。
(Chemical Equation Presented) An open relationship: The triethylborane/O2-mediated addition of xanthates to vinyl epoxides and derivatives represents an efficient process to form carbon-carbon bonds. Complex structures can be rapidly assembled in a modular, convergent manner, under mild conditions, using readily available reagents (see scheme, Bn = benzyl). The formation of quaternary centers proved especially facile. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.