Progression of SARS-CoV-2 Seroprevalence in St. Louis, Missouri, through January 2021.
Progression of SARS-CoV-2 Seroprevalence in St. Louis, Missouri, through January 2021.
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DOI：
10.1128/msphere.00450-21
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发表时间：
2021-08-25
期刊：
影响因子：
4.8
通讯作者：
Fremont DH
中科院分区：
文献类型：
--
作者：
Smith BK;Janowski AB;Fremont AC;Adams LJ;Dai YN;Farnsworth CW;Gronowski AM;Roper SM;Wang D;Fremont DH
对2020年7月、2020年11月或2021年1月期间在密苏里州圣路易斯市的医院就诊的3,066名个体进行了严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）血清阳性评估。儿童血清阳性率从7月的5.22%上升到1月的21.16%。在同一时期，在开始大规模疫苗接种之前，成人血清阳性率从4.52%上升到19.03%。重要性本研究确定了在2020年7月至2021年1月的三个采集期内，来自密苏里州圣路易斯大都会区的儿童和成人样本中携带SARS-CoV-2抗体的百分比。截至2021年1月，20.68%的受检个体有抗体。这些结果显示了密苏里州圣路易斯的SARS-CoV-2大流行的演变，并提供了大规模疫苗接种开始前感染程度的快照。
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seropositivity was assessed for 3,066 individuals visiting hospitals in St. Louis, Missouri, during July 2020, November 2020, or January 2021. Seropositivity in children increased from 5.22% in July to 21.16% in January. In the same time frame, seropositivity among adults increased from 4.52% to 19.03%, prior to initiation of mass vaccination. IMPORTANCE This study determined the percentage of children and adult samples from the St. Louis metropolitan area in Missouri with SARS-CoV-2 antibodies during three collection periods spanning July 2020 to January 2021. By January 2021, 20.68% of the tested individuals had antibodies. These results show the evolution of the SARS-CoV-2 pandemic in St. Louis, Missouri, and provide a snapshot of the extent of infection just prior to the start of mass vaccination.