Protection of the skin of mice against irradiation with cyclotron-accelerated helium ions by 2-mercaptoethylamine.
Protection of the skin of mice against irradiation with cyclotron-accelerated helium ions by 2-mercaptoethylamine.
复制标题
2-巯基乙胺保护小鼠皮肤免受回旋加速器加速氦离子的照射。
DOI：
10.3109/02841867509132698
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发表时间：
1975
期刊：
影响因子：
--
通讯作者：
J. Leith
中科院分区：
文献类型：
--
作者：
D. Baker;J. Leith
使用模态 LET 为每微米 15 keV 的氦离子束，将小鼠皮肤暴露于 1 250 至 3 000 拉德的剂量下。在照射前 15 分钟，对局部涂抹 10% MEA 乳霜基质或安慰剂的小鼠进行皮肤反应评估。皮肤反应的比较表明，MEA 处理导致 DMF 至少为 1.2。讨论了放射治疗的意义。
Mouse skin was exposed to doses of 1 250 to 3 000 rad using a helium ion beam with modal LET of 15 keV per micron. The skin reactions were evaluated for mice treated with a topical application of 10% MEA in a cream base or a placebo 15 minutes before irradiation. A comparison of the skin reactions indicated that the MEA treatment resulted in a DMF of at least 1.2. The implication for radiation therapy was discussed.