Morphological Spectra of Adult Human Stellate Ganglia: Implications for Thoracic Sympathetic Denervation.
Morphological Spectra of Adult Human Stellate Ganglia: Implications for Thoracic Sympathetic Denervation.
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DOI：
10.1002/ar.23797
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发表时间：
2018-07
期刊：
影响因子：
--
通讯作者：
Ajijola OA
中科院分区：
文献类型：
--
作者：
Kwon OJ;Pendekanti S;Fox JN;Yanagawa J;Fishbein MC;Shivkumar K;Lambert HW;Ajijola OA
心脏交感神经（CSD）以治疗心室心律不齐（VAS）需要在星状（子宫胸部）神经节的中部或下三分之一的转换（SG）。
确定左右SG（LSG和RSG）的形态以及内部的SOMATA分布。
从14个尸体尸体中解剖的LSG和RSG（n = 28）是完整的。
对受试者的平均年龄为13岁，男性为5/14在RSG中最常见（8/14），虽然融合，但在LSG中最常见（8/14）。 RSG缺乏融合的外观，而LSG的28.6％在组织学上出现，在融合的圆形神经节中看到了一个焦点，而融合的延长SG则分布在整个somata中。
SG以三种主要形式出现，并包含较大的研究的不同分布，以定义总体解剖结构与神经元SOMATA分布之间的关系，以提高CSD治疗VAS的效率。
Cardiac sympathetic denervation (CSD) to treat ventricular arrhythmias (VAs) requires transection at the middle or lower third of stellate (cervicothoracic) ganglia (SG). However, the morphological appearance of the adult SG and distribution of neuronal somata within it are not well described. To determine the morphology of left and right SG (LSG and RSG) and the distribution of somata within. LSG and RSG (n=28) from 14 embalmed adult cadavers were dissected intact. Weight, volume, height, morphologic appearance, relationship between C8 and T1 ganglia (which form the SG) were determined, along with histology. Demographics, history of cardiac disease, and cause of death were also reviewed. Mean age of the subjects was 76±13 years, and 5/14 were male. Three distinct morphologies of SG were identified: fusiform-rounded; fusiform-elongated; and bi-lobed. RSG and LSG did not differ in weight or volume. RSG were longer than LSG (2.05±0.28cm vs. 1.66±0.47cm, p=0.024). Bi-lobed morphology was most common in RSGs (8/14), while fused, elongated was most common in LSG (8/14). RSGs lacked fused, rounded appearance, while 28.6% of LSG appeared as such. Histologically, one focus of somata was seen in fused rounded ganglia, while fused elongated SG had somata distributed throughout. Bi-lobed SG demonstrated two foci of somata, with the interconnecting stalk containing sparse somata. SG appear in three major forms and contain varying distributions of somata. Larger studies are warranted to define the relationship between gross anatomy and distribution of neuronal somata to improve the efficacy of CSD in treating VAs.
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影响因子：
2.4
作者：
Saylam, Canan Y.;Ozgiray, Erkin;Zileli, Mehmet
通讯作者：
Zileli, Mehmet
DOI：
10.1161/circep.112.972836
发表时间：
2012-10
期刊：
Circulation. Arrhythmia and electrophysiology
影响因子：
--
作者：
Ajijola OA;Wisco JJ;Lambert HW;Mahajan A;Stark E;Fishbein MC;Shivkumar K
通讯作者：
Shivkumar K
影响因子：
2.4
作者：
Pather, N;Partab, P;Satyapal, KS
通讯作者：
Satyapal, KS
影响因子：
--
作者：
Kuntz, Albert
通讯作者：
Kuntz, Albert
影响因子：
2.8
作者：
MOCK, C J;JULIAN, O C
通讯作者：
JULIAN, O C