C-13 NUCLEAR MAGNETIC-RESONANCE SPIN-LATTICE RELAXATION IN N-ACYLNEURAMINIC ACIDS - PROBES FOR INTERNAL DYNAMICS AND CONFORMATIONAL-ANALYSIS
C-13 NUCLEAR MAGNETIC-RESONANCE SPIN-LATTICE RELAXATION IN N-ACYLNEURAMINIC ACIDS - PROBES FOR INTERNAL DYNAMICS AND CONFORMATIONAL-ANALYSIS
复制标题
DOI：
10.1021/ja00467a025
复制
发表时间：
1977-01-01
影响因子：
15
通讯作者：
THORNTON, ER
中科院分区：
文献类型：
--
作者：
CZARNIECKI, MF;THORNTON, ER
对几种 N-酰基神经氨酸衍生物进行了 13C NMR 研究。自旋晶格弛豫时间（NT1DD =约0.3秒）表明吡喃糖环C经历各向同性旋转，并且C-7和C-8（但不是C-9）与环各向同性。弛豫数据支持涉及分子内氢键网络的模型。非质子化 C 的 T1DD 计算值与实验非常吻合。
13C NMR studies of several N-acylneuraminic acid derivatives were made. Spin-lattice relaxation times (NT1DD = about 0.3 s) indicate that the pyranose ring C undergo isotropic rotation and that C-7 and C-8, but not C-9, are isotropic with the ring. A model involving an intramolecular H-bond network is supported by the relaxation data. Calculated values of T1DD for nonprotonated C agree closely with experiment.