Sarcoidal-type allergic contact granuloma: a rare complication of ear piercing.
Sarcoidal-type allergic contact granuloma: a rare complication of ear piercing.
复制标题
结节样过敏性接触性肉芽肿：一种罕见的耳穿孔并发症。
DOI：
10.1097/00000372-200402000-00008
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
N. Hunzelmann
中科院分区：
文献类型：
--
作者：
C. Casper;W. Groth;N. Hunzelmann
随着身体穿孔越来越流行，并发症也在增加。这种病变的活组织检查可能会给复查的皮肤病理学家带来特殊的问题。我们提出了两个病人谁发展丘疹样病变在耳洞的地方。出乎意料的是，结果包括明显的结节状肉芽肿形成，并伴有纤维蛋白样坏死。排除了感染性病因。然而，斑贴试验显示对钯、铂和镍有接触性过敏。有趣的是，斑贴试验部位的组织病理学检查也显示肉芽肿形成。这些发现提示病变为过敏性接触性肉芽肿。当在穿刺部位的皮肤活检中遇到这种特殊类型的组织反应时，复查皮肤病理学家应考虑过敏反应的可能性。仔细的病史和彻底的诊断程序，包括斑贴试验部位的活检，可以确定接触性过敏性肉芽肿的诊断。
As body piercing is increasingly en vogue, complications are on the rise as well. Biopsies of such lesions can impose special problems to the reviewing dermatopathologist. We present two patients who developed papulonodular lesions at the sites of ear piercings. Unexpectedly, the findings included prominent sarcoidal granuloma formation with confluent areas of fibrinoid necrosis. An infectious etiology was excluded. However, patch testing revealed contact allergy to palladium, platinum, and nickel. Interestingly, histopathologic examination of the patch test sites also demonstrated granuloma formation. These findings suggest that the lesions represent allergic contact granulomas. When confronted with this special type of tissue reaction in skin biopsies of piercing sites, the reviewing dermatopathologist should consider the possibility of an allergic reaction. Careful history and thorough diagnostic procedures, including biopsy of the patch test site can establish the diagnosis of contact allergic granuloma.