Suppressed cytotoxic T lymphocyte responses in experimental cysticercosis.
Suppressed cytotoxic T lymphocyte responses in experimental cysticercosis.
复制标题
抑制实验性囊尾蚴病中的细胞毒性 T 淋巴细胞反应。
DOI：
10.1016/s0304-4017(02)00105-x
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发表时间：
2002
影响因子：
2.6
通讯作者：
Kuhn,RE
中科院分区：
文献类型：
--
作者：
Spolski,RJ;Alexander-Miller,MA;Kuhn,RE
有丝分裂原诱导的T细胞反应在感染了粗头绦虫幼虫的小鼠中被抑制。然而，实验性感染对特异性T细胞应答的影响尚未得到研究。在本研究中，我们证明，幼虫感染的小鼠表现出抑制能力，发展抗病毒特异性细胞毒性T淋巴细胞（CTL）反应，同时保持明显正常的自然杀伤（NK）细胞的反应。
Mitogen-induced T cell responses are suppressed in mice infected with larvae of Taenia crassiceps. The effects of experimental infection on specific T cell responses, however, have not been examined. In the present study, we demonstrate that larval-infected mice exhibit suppressed ability to develop anti-virus specific cytotoxic T lymphocyte (CTL) responses while maintaining apparently normal natural killer (NK) cell responsiveness.