Vaccine-related pain: randomised controlled trial of two injection techniques
Vaccine-related pain: randomised controlled trial of two injection techniques
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DOI：
10.1136/adc.2007.118695
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发表时间：
2007-12-01
影响因子：
5.2
通讯作者：
Parkin, Patricia C.
中科院分区：
文献类型：
--
作者：
Ipp, Moshe;Taddio, Anna;Parkin, Patricia C.
目的：比较使用缓慢标准护理注射技术与快速实用技术的婴儿免疫期间的急性疼痛反应。设计：随机对照试验。设置：单中心、城市儿科初级保健实践。受试者：接受常规 DPTaP-Hib 免疫接种的 4-6 个月大的健康婴儿。干预措施：标准护理组：注射前缓慢抽吸、缓慢注射和缓慢撤药。实用组：无误吸、快速注射和快速撤药。主要结果指标：通过改良行为疼痛量表（MBPS）测量婴儿即时疼痛、哭闹和家长/儿科医生视觉模拟量表（VAS）。结果：113名婴儿参与；年龄、出生顺序或既往镇痛使用情况没有观察到差异。平均 MBPS 分数（95% 置信区间 (Cl)）较高 (p
Objective: To compare acute pain response during immunisation in infants using a slow standard of care injection technique versus a rapid pragmatic technique.Design: Randomised controlled trial.Setting: Single-centre, urban paediatric primary care practice.Subjects: Healthy infants 4-6 months of age receiving their routine DPTaP-Hib immunisation.Interventions: Standard of care group: slow aspiration prior to injection, slow injection and slow withdrawal. Pragmatic group: no aspiration, rapid injection and rapid withdrawal.Main outcome measures: Immediate infant pain measured by the Modified Behavior Pain Scale (MBPS), crying and parent/paediatrician visual analogue scale (VAS).Results: 113 infants participated; there were no observed differences in age, birth order or prior analgesic use. Mean MBPS scores (95% confidence interval (Cl)) were higher (p