Sex differences in carbohydrate metabolism
Sex differences in carbohydrate metabolism
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DOI：
10.1097/00075197-200111000-00010
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发表时间：
2001-11-01
影响因子：
3.1
通讯作者：
Ruby, BC
中科院分区：
文献类型：
--
作者：
Tarnopolsky, MA;Ruby, BC
在亚极限耐力运动中，女性比男性氧化更多的脂质和更少的碳水化合物作为代谢底物。这反映在与男性相比，女性骨骼肌的糖原利用率较低，肝糖产量也较低。后一种观察结果可以解释在女性耐力运动中观察到的较低亮氨酸氧化。动物和初步人体研究证据表明，17- β -雌二醇可能是运动期间碳水化合物代谢性别二态反应的主要决定因素。从实际的角度来看，女性在体育赛事前四天增加饮食能量摄入（以及碳水化合物摄入的百分比），以超补偿肌糖原浓度，这似乎是必要的。碳水化合物代谢的性别差异可能对糖尿病患者和先天性脂质代谢错误的护理有未来的意义。临床与护理杂志(4):521-526。(C) 2001利平科特·威廉姆斯·威尔金斯。
During submaximal endurance exercise, women oxidize more lipid and less carbohydrate as metabolic substrates than men. This is reflected in a lower glycogen utilization in skeletal muscle and lower hepatic glucose production for women compared with men. These latter observations may explain the lower leucine oxidation observed during endurance exercise in women. Animal and preliminary human study evidence suggests that 17-beta-estradiol may be a major determinant of the sex dimorphic response in carbohydrate metabolism during exercise. From a practical standpoint, it appears necessary for women to increase their dietary energy intake (and percentage derived from carbohydrates) for four days before a sporting event in order to supercompensate muscle glycogen concentrations. Sex differences in carbohydrate metabolism may have future implications for the care of patients with diabetes and inborn errors of lipid metabolism. Curr Opin Clin Nutr Metab Care 4:521-526. (C) 2001 Lippincott Williams Wilkins.