VENTRICULAR SYSTOLIC PRESSURE-VOLUME AREA AS PREDICTOR OF CARDIAC OXYGEN-CONSUMPTION
VENTRICULAR SYSTOLIC PRESSURE-VOLUME AREA AS PREDICTOR OF CARDIAC OXYGEN-CONSUMPTION
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DOI：
10.1152/ajpheart.1981.240.1.h39
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发表时间：
1981-01-01
影响因子：
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通讯作者：
SHIRAHATA, M
中科院分区：
文献类型：
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作者：
SUGA, H;HAYASHI, T;SHIRAHATA, M
用一种改进的耗氧率（VO 2）测定方法，研究了犬左心室收缩期压力-容积面积（PVA）与心脏耗氧率（VO 2）的相关性。PVA是由收缩末期和舒张末期PV线以及PV环的收缩段界定的压力-容积（PV）平面中的比面积。与以往将等容收缩和射血收缩的VO 2-PVA数据合并进行分析不同，本文分别研究了两种不同模式的VO 2-PVA数据，以考察它们之间的VO 2-PVA关系是否存在差异。等容收缩和射血收缩时，PVA上VO 2的线性回归基本相同。PVA显然是一个可靠的预测VO 2，无论在一个给定的左心室收缩模式与稳定的变力性背景。
The recently reported correlation between the canine left ventricular systolic pressure-volume area (PVA) and cardiac O2 consumption rate/beat (VO2) was studied by an improved method of VO2 assessment. PVA is the specific area in the pressure-volume (PV) plane bounded by the end-systolic and end-diastolic PV lines and the systolic segment of the PV loop. Different from the previous study in which VO 2-PVA data from isovolumic and ejecting contractions were pooled for analyses, VO2-PVA data from the 2 different modes was studied separately to examine whether there was any difference of VO2-PVA relationship between them. The linear regressions of VO2 on PVA were virtually the same for isovolumic and ejecting contractions. PVA apparently serves as a reliable predictor of VO2 regardless of the mode of contraction in a given left ventricle with a stable inotropic background.