Impact of energy turnover on fat balance in healthy young men during energy balance, energetic restriction and overfeeding
Impact of energy turnover on fat balance in healthy young men during energy balance, energetic restriction and overfeeding
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DOI：
10.1017/s0007114519002551
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发表时间：
2020-01-14
影响因子：
3.6
通讯作者：
Bosy-Westphal, Anja
中科院分区：
文献类型：
--
作者：
Nas, Alessa;Buesing, Franziska;Bosy-Westphal, Anja
人们认为，当身体活动和能量摄入都很高时（高能量周转率），体重控制会得到改善。本研究的目的是研究ET在零能量平衡（EB）、能量限制（ER）和过度摄食（of）期间对脂肪平衡的短期影响。在一个随机交叉研究中,9名健康男性(BMI: 23中心点0 (SD 2中心点1)千克/米(2),26个中心点6点5)(SD 3中心年)通过3 x 3 d代谢室:三个级别的ET(低、中、高,体力活动水平点3 - 1中心点4 = 1中心,中心6点5 - 1中心点和1点7 - 1中心点8)进行零EB, ER和(100年、75年和125%的个人能量需求)。在跑步机上（0,165和330 min）以4 km/h的速度行走，获得了不同水平的ET。计算24小时宏量营养素氧化和相对宏量营养素平衡（相对于摄入的氧化），并分析NEFA、24小时胰岛素和儿茶酚胺分泌作为脂肪氧化的决定因素。在EB和OF期间，24小时脂肪氧化随着ET的增加而增加。这导致中等ET （EB: + 17%, OF: + 14%）和高ET （EB: + 23%, OF: + 17%）时的相对脂肪平衡高于低ET（均P < 0中心点0.05）。相比之下，内质网导致24小时脂肪氧化的刺激，而与ET无关（ET水平之间的相对脂肪平衡没有差异，P > 0中心点05）。总之，在高度控制的条件下，与久坐状态相比，较高的ET改善了年轻健康男性在OF和EB期间的相对脂肪平衡。
Body weight control is thought to be improved when physical activity and energy intake are both high (high energy turnover (ET)). The aim of the present study was to investigate the short-term impact of ET on fat balance during zero energy balance (EB), energetic restriction (ER) and overfeeding (OF). In a randomised crossover study, nine healthy men (BMI: 23 center dot 0 (SD 2 center dot 1) kg/m(2), 26 center dot 6 (SD 3 center dot 5) years) passed 3 x 3 d in a metabolic chamber: three levels of ET (low, medium and high; physical activity level = 1 center dot 3-1 center dot 4, 1 center dot 5-1 center dot 6 and 1 center dot 7-1 center dot 8) were performed at zero EB, ER and OF (100, 75 and 125 % of individual energy requirement). Different levels of ET were obtained by walking (4 km/h) on a treadmill (0, 165 and 330 min). Twenty-four-hour macronutrient oxidation and relative macronutrient balance (oxidation relative to intake) was calculated, and NEFA, 24-h insulin and catecholamine secretion were analysed as determinants of fat oxidation. During EB and OF, 24-h fat oxidation increased with higher ET. This resulted in a higher relative fat balance at medium ET (EB: +17 %, OF: +14 %) and high ET (EB: +23 %, OF: +17 %) compared with low ET (all P < 0 center dot 05). In contrast, ER led to a stimulation of 24-h fat oxidation irrespective of ET (no differences in relative fat balance between ET levels, P > 0 center dot 05). In conclusion, under highly controlled conditions, a higher ET improved relative fat balance in young healthy men during OF and EB compared with a sedentary state.