A case of tooth autotransplantation after long-term cryopreservation using a programmed freezer with a magnetic field
A case of tooth autotransplantation after long-term cryopreservation using a programmed freezer with a magnetic field
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DOI：
10.2319/030314-148.1
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发表时间：
2015-05-01
影响因子：
3.4
通讯作者：
Tanimoto, Kotaro
中科院分区：
文献类型：
--
作者：
Kaku, Masato;Shimasue, Hiroshi;Tanimoto, Kotaro
本病例报告描述了治疗骨性III类错牙合与自体移植的冷冻保存的牙齿。为了获得美观的面部轮廓和良好的咬合，选择拔除双颌前磨牙和手术治疗。患者左下第一磨牙有慢性根尖周炎。虽然她没有感觉到该区域有任何疼痛，但这颗牙齿被认为预后不良。因此，我们冷冻保存拔除的前磨牙，准备自体移植在较低的第一磨牙区，因为牙齿可能需要在未来删除。将牙齿通过开发用于组织冷冻保存的具有磁场的程序化冷冻机（CAS冷冻机）冷冻，并在-150 ℃深冷冻机中冷冻保存。经过1.5年的术前正畸治疗，双侧下颌升支矢状劈开截骨术治疗下颌骨后退。在固位期，面部轮廓和咬合得到改善。第一次就诊后6年，患者左下第一磨牙疼痛，并观察到排脓，因此我们拔除了左下第一磨牙，并自体移植了冷冻保存的前磨牙。三年后，在自体移植牙处观察到健康的牙周组织。这个病例报告表明，长期冷冻保存的牙齿由CAS冰箱是有用的，以后自体移植，这可能是一个可行的技术，以取代缺失的牙齿。
This case report describes the treatment of a skeletal Class III malocclusion with autotransplantation of a cryopreserved tooth. To gain an esthetic facial profile and good occlusion, extraction of bimaxillary premolars and surgical therapy were chosen. The patient had chronic apical periodontitis on the lower left first molar. Although she did not feel any pain in that region, the tooth was considered to have a poor prognosis. Therefore, we cryopreserved the extracted premolars to prepare for autotransplantation in the lower first molar area because the tooth would probably need to be removed in the future. The teeth were frozen by a programmed freezer with a magnetic field (CAS freezer) that was developed for tissue cryopreservation and were cryopreserved in -150 degrees C deep freezer. After 1.5 years of presurgical orthodontic treatment, bilateral sagittal split ramus osteotomy was performed for mandible setback. Improvement of the facial profile and the occlusion were achieved in the retention phase. Six years after the initial visit, the patient had pain on the lower left first molar, and discharge of pus was observed, so we extracted the lower left first molar and autotransplanted the cryopreserved premolar. Three years later, healthy periodontium was observed at the autotransplanted tooth. This case report suggests that long-term cryopreservation of teeth by a CAS freezer is useful for later autotransplantation, and this can be a viable technique to replace missing teeth.