Symmetrical development of pigmentation as a specific feature of the fundus pattern in retinitis pigmentosa.
Symmetrical development of pigmentation as a specific feature of the fundus pattern in retinitis pigmentosa.
复制标题
色素沉着的对称发展是色素性视网膜炎眼底模式的一个具体特征。
DOI：
10.1016/0002-9394(63)90186-7
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发表时间：
1963
影响因子：
4.2
通讯作者：
I. Biró
中科院分区：
文献类型：
--
作者：
I. Biró
区分色素性视网膜炎与某些类型的双侧绒毛膜视网膜炎并不容易。此外，视网膜损伤后也可能发生与色素性视网膜炎相似的眼底变化。本报告不打算讨论鉴别诊断的所有细节；然而，要注意色素沉着的对称发展，这是诊断中非常重要的特征。眼点。在许多病例中发现，通常被认为仅仅是神经上皮破坏的后果的色素沉着并不总是循环开始的。通常，它首先出现在两个眼底相应的限定位置。除了极少数单侧受累的病例外，该疾病通常同时影响眼底，其强度相同，值得注意的是，色素沉着往往出现在眼底的相同部位。不幸的是，患者通常只有在色素性视网膜炎的临床和眼底变化已经明显时才寻求建议。当然，在这种情况下，早期诊断和早期症状都无法描述。事实上，几乎只有已知父母患有色素性视网膜炎作为家族性疾病（通常是显性遗传）的儿童才能研究该疾病的早期阶段和早期变化。
Differentiating retinitis pigmentosa from certain types of bilateral chorioretinitis is not always easy. Moreover, fundus changes similar to those seen in retinitis pigmentosa may also develop after injury to the retina. This report does not intend to go into al1 the details of differential diagnosis; attention is called, however, to the symmetrical development of pigmentation which is a highly important feature in the diagnosis. pigmentosa. It has been found in many cases that pigmentation, which is commonly considered simply a sequel to the destruction of the neuro-epithelium, does not always begin circularly. Frequently, it makes its first appearance at corresponding circumscribed sites of the two eyegrounds.Except in the very few cases of unilateral involvement the disease usually affects the eyegrounds simultaneously, with equal intensity and, significantly, the pigmentation tends to appear+ at identical sites on the fundus. Unfortunately, the patients usually seek advice only when the clinical and fundus changes of retinitis pigmentosa are already marked. In such cases, of course, neither early diagnosis nor early symptoms can be described. As a matter of fact, it is almost exclusively in children of parents known to have retinitis pigmentosa as a familial disease (usually dominant inheritante) that the early stages and early changes of the disease can be studied.