Tris(pentafluorophenyl)borane and Beyond: Modern Advances in Borylation Chemistry
Tris(pentafluorophenyl)borane and Beyond: Modern Advances in Borylation Chemistry
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DOI：
10.1021/acs.inorgchem.6b02911
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发表时间：
2017-08-07
影响因子：
4.6
通讯作者：
Melen, Rebecca L.
中科院分区：
文献类型：
--
作者：
Lawson, James R.;Melen, Rebecca L.
随着主族化学，特别是硼化学在过去20年中的扩大和发展，一种试剂也开始崭露头角。三(五氟苯基)硼烷，B(C6F5)(3)(俗称BCF)，在硼化、氢化、硅氢化等反应中有着广泛的应用。受挫Lewis对(FLP)化学、Lewis酸催化等：B(C6F5)(3)的高Lewis酸度源于其三个C6F5环的电子效应，使其成为大量反应的多功能试剂。此外，这些环的立体结构还允许它作为FLP中的Lewis酸，使该试剂具有另一种有用的合成应用。然而，随着主基化学作为一个领域的不断发展，需要超越BCF的新试剂，不仅增加了可用反应的范围，而且增加了可获得的化合物的广度。为了完成这一任务，已经取得了很大的进展，本综述将重点介绍与硼化反应有关的硼化学的现代进展。在这里，我们将展示B(C6F5)(3)在硼化反应中的最新用途，同时也集中在新的硼烷和硼盐用途方面的最新进展，这些用途使坚固的B(C6F5)(3)黯然失色。
As main-group chemistry, in particular boron chemistry, has expanded and developed over the past 20 years, one reagent has risen to prominence as well. Tris(pentafluorophenyl)borane, B(C6F5)(3) (commonly known as BCF), has demonstrated extensive applications in a wide variety of reactions, including borylation, hydrogenation, hydrosilylation,. frustrated Lewis pair (FLP) chemistry, Lewis acid catalysis, and more: The high Lewis acidity of B(C6F5)(3) is derived from the electronic effects of its three C6F5 rings, rendering it a versatile reagent for a great number of reactions. In addition, the steric bulk of these rings also allows it to function as the Lewis acid in a FLP, granting this reagent yet another synthetically useful application. However, as main-group chemistry continues to, evolve as a field, new reagents are, required that go beyond BCF, increasing not only the range of reactions available but also the breadth of compounds attainable. Great strides have already been made in order to accomplish this task, and this review will highlight modern advances in boron chemistry relating to borylation reactions. Herein, we will show the recent uses of B(C6F5)(3) in borylation reactions while also focusing on current advances in novel borane and borocation usage that eclipses that of the stalwart B(C6F5)(3).