Characterizing the contrast of white matter and grey matter in high-resolution phase difference enhanced imaging of human brain at 3.0 T
Characterizing the contrast of white matter and grey matter in high-resolution phase difference enhanced imaging of human brain at 3.0 T
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3.0 T 下人脑高分辨率相位差增强成像中白质和灰质对比度的表征
DOI：
10.1007/s00330-014-3480-7
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发表时间：
2014
影响因子：
5.9
通讯作者：
Guangbin Wang
中科院分区：
文献类型：
--
作者：
Li Yang;Shanshan Wang;Bin Yao;Lili Li;Xiaofei Xu;Lingfei Guo;Lianxin Zhao;Xinjuan Zhang;Weibo Chen;Q. Chan;Guangbin Wang
AbstractObjectivesThis study was address the pathway of characterizing contrast between and within grey matter and白色matter using the phase difference enhancement（PADRE）technique.MethodsPADRE imaging was performed in 33例健康志愿者.血管增强（VE），组织增强（TE），和PADRE图像从源图像重建，并进行了评价方面的分化的灰色到白色物质界面，纹的Gennari，和两个层，内部矢状层（ISS）和外部矢状层（ESS），opticalradiation. Results白色物质区域显示信号强度下降相比，灰质区域。在TE图像中，白色物质和皮质灰质之间的区分比在PADRE图像中更清晰，但在VE图像中显示较差。在所有三个图像集上均观察到Gennari纹。TE和PADRE图像上显示的低信号强度带代表视放射线，在TE和PADRE图像上被划分为两个不同信号强度的层。额叶灰质和白色物质之间以及ISS和ESS之间的相移存在统计学显著差异结论PADRE技术能识别灰-白色界面、Gennari纹、ISS和ESS，与VE图像相比，PADRE和TE图像的对比度得到改善。关键点·相位差增强（PADRE）成像可以在组织之间产生不同的对比
·PADRE技术利用固有的磁磁化率变化
· PADRE MR成像可更好地显示体内某些脑解剖结构
· PADRE成像能够描绘初级视觉皮层中的Gennari纹
· PADRE成像能够识别两个光学辐射层
AbstractObjectivesThe purpose of this study was to address the feasibility of characterizing the contrast both between and within grey matter and white matter using the phase difference enhanced (PADRE) technique.MethodsPADRE imaging was performed in 33 healthy volunteers. Vessel enhancement (VE), tissue enhancement (TE), and PADRE images were reconstructed from source images and were evaluated with regard to differentiation of grey-to-white matter interface, the stria of Gennari, and the two layers, internal sagittal stratum (ISS) and external sagittal stratum (ESS), of optic radiation.ResultsWhite matter regions showed decreased signal intensity compared to grey matter regions. Discrimination was sharper between white matter and cortical grey matter in TE images than in PADRE images, but was poorly displayed in VE images. The stria of Gennari was observed on all three image sets. Low-signal-intensity bands displayed in VE images representing the optic radiation were delineated as two layers of different signal intensities in TE and PADRE images. Statistically significant differences in phase shifts were found between frontal grey and white matter, as well as between ISS and ESS (p < 0.01).ConclusionsThe PADRE technique is capable of identifying grey-to-white matter interface, the stria of Gennari, and ISS and ESS, with improved contrast in PADRE and TE images compared to VE images.Key Points• Phase difference enhanced (PADRE) imaging can yield diverse contrasts between tissues
• The PADRE technique utilizes the inherent variety of magnetic susceptibilities
• PADRE MR imaging provides better visualization of certain cerebral anatomy in vivo
• PADRE imaging is able to delineate the stria of Gennari in the primary visual cortex
• PADRE imaging is able to identify the two optic radiation layers
影响因子：
19.7
作者：
Kundel, HL;Polansky, M
通讯作者：
Polansky, M