Impulsivity and methamphetamine use

Impulsivity and methamphetamine use
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DOI:
10.1016/j.jsat.2005.05.001
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发表时间:
2005-09-01
影响因子:
3.9
通讯作者:
Patterson, TL
Patterson, TL
中科院分区:
医学2区
文献类型:
--
作者:
Semple, SJ;Zians, J;Patterson, TL

文献摘要

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本研究的目的是探讨甲基苯丙胺(冰毒)的使用和冲动之间的关系,在385个艾滋病毒阴性的异性恋识别冰毒用户的样本。在自我报告的冲动性测量中得分最高的参与者与那些在背景特征,冰毒使用模式,酒精和其他非法药物的使用,性风险行为和精神健康变量方面得分较低的参与者进行了比较。与低冲动组相比,高冲动组的甲基苯丙胺使用者更年轻,受教育程度更低,使用更多的甲基苯丙胺,更有可能成为狂欢用户,有更多的性伴侣,从事更多无保护的阴道和口交,并且在贝克抑郁量表上得分更高。在逻辑回归分析中,贝克抑郁症是最能区分在冲动性方面得分高和得分低的冰毒使用者的因素。神经生理学途径,可能是冲动和冰毒使用之间的关系进行了讨论。(c)2005年爱思唯尔公司All rights reserved.
The purpose of this study was to explore the relationship between methamphetamine (meth) use and impulsivity in a sample of 385 HIV-negative heterosexually identified meth users. Participants who scored highest on a self-report measure of impulsivity were compared with those who scored lower in terms of background characteristics, meth use patterns, use of alcohol and other illicit drugs, sexual risk behavior, and psychiatric health variables. Methamphetamine users in the high impulsivity group were younger, less educated, used larger quantities of meth, were more likely to be binge users, had a larger number of sexual partners, engaged in more unprotected vaginal and oral sex, and scored higher on the Beck Depression Inventory as compared with those in the low impulsivity group. In a logistic regression analysis, Beck depression was the factor that best distinguished between meth users who scored high and those who scored low on impulsivity. Neurophysiological pathways that may underlie the relationship between impulsivity and meth use are discussed. (c) 2005 Elsevier Inc. All rights reserved.