Children's intellectual ability is associated with structural network integrity.
Children's intellectual ability is associated with structural network integrity.
复制标题
DOI：
10.1016/j.neuroimage.2015.09.012
复制
发表时间：
2016-01-01
期刊：
影响因子：
5.7
通讯作者：
Hetrick WP
中科院分区：
文献类型：
--
作者：
Kim DJ;Davis EP;Sandman CA;Sporns O;O'Donnell BF;Buss C;Hetrick WP
最近对成年人的结构和功能神经成像研究表明，有效的大脑连接模式是人类智力的基础。具体地说，具有有效的小世界组织的全脑网络以及特定的大脑区域(即顶额整合理论，P-Fit)似乎与智力有关。然而，这些关系还没有在使用结构网络测量的儿童中进行研究。这项横断面研究考察了99名典型发育的健康青春期前儿童的非语言智力与结构网络组织之间的关系。我们发现网络的整体效率和智力之间存在着很强的正相关关系，其中视觉空间运动加工的分测验(方块设计，BD)在整体大脑结构和P-FIT中包含的局部区域以及与图案和形状加工有关的临时区域中都是显著的。BD还与丰富的俱乐部组织有关，包括额区、枕区、颞区、海马区和新纹状体。这表明，儿童的视觉构建能力与儿童大脑整体和局部整合的效率显著相关。我们的发现表明，视觉构建和推理可能会对大脑的全局整合加工产生普遍要求。
Recent structural and functional neuroimaging studies of adults suggest that efficient patterns of brain connectivity are fundamental to human intelligence. Specifically, whole brain networks with an efficient small-world organization, along with specific brain regions (i.e., Parieto-Frontal Integration Theory, P-FIT) appear related to intellectual ability. However, these relationships have not been studied in children using structural network measures. This cross-sectional study examined the relation between non-verbal intellectual ability and structural network organization in 99 typically developing healthy preadolescent children. We showed a strong positive association between the network’s global efficiency and intelligence, in which a subtest for visuo-spatial motor processing (Block Design, BD) was prominent in both global brain structure and local regions included within P-FIT as well as temporal regions involved with pattern and form processing. BD was also associated with rich club organization, which encompassed frontal, occipital, temporal, hippocampal, and neostriatal regions. This suggests that children’s visual construction ability is significantly related to how efficiently children’s brains are globally and locally integrated. Our findings indicate that visual construction and reasoning may make general demands on globally integrated processing by the brain.