Three-dimensional phase optical transfer function in axially symmetric microscopic quantitative phase imaging
Three-dimensional phase optical transfer function in axially symmetric microscopic quantitative phase imaging
复制标题
DOI：
10.1364/josaa.403861
复制
发表时间：
2020-12-01
影响因子：
1.9
通讯作者：
Gaylord, Thomas K.
中科院分区：
文献类型：
--
作者：
Huang, Jianhui;Bao, Yijun;Gaylord, Thomas K.
三维定量相位成像(3DQPI)被广泛认为是一种潜在的高影响的显微成像方式。决定3D QPI分辨率的核心是位相光学传递函数(POTF)。POTF在其空间频率覆盖范围(SFC)上的大小指定了每个允许空间频率的响应强度。本文对轴对称光学结构的POTF进行了详细的分析。首先，提出了一种有用的对证监会的几何解释，使其能够可视化。其次，推导出了一般非傍轴情况下POTF的一维积分表达式，从而可以快速地计算POTF。第三，该公式适用于圆盘、环形、多环形和高斯照明以及环形物镜。综上所述，这些贡献使得三维轴对称POTF的可视化和简化计算成为可能，并为在广泛的应用中优化QPI提供了基础。(C)2020年美国光学学会
Three-dimensional quantitative phase imaging (3D QPI) is widely recognized as a potentially high-impact microscopic modality. Central to determining the resolution capability of 3D QPI is the phase optical transfer function (POTF). The magnitude of the POTF over its spatial frequency coverage (SFC) specifies the intensity of the response for each allowed spatial frequency. In this paper, a detailed analysis of the POTF for an axially symmetric optical configuration is presented. First, a useful geometric interpretation of the SFC, which enables its visualization, is presented. Second, a closed-form 1D integral expression is derived for the POTF in the general nonparaxial case, which enables rapid calculation of the POTF. Third, this formulation is applied to disk, annular, multi-annuli, and Gaussian illuminations as well as to an annular objective. Taken together, these contributions enable the visualization and simplified calculation of the 3D axially symmetric POTF and provide a basis for optimizing QPI in a wide range of applications. (c) 2020 Optical Society of America