THE PROJECTION OF SENSORY NEURONS IN THE CENTRAL NERVOUS-SYSTEM OF DROSOPHILA - CHOICE OF THE APPROPRIATE PATHWAY

THE PROJECTION OF SENSORY NEURONS IN THE CENTRAL NERVOUS-SYSTEM OF DROSOPHILA - CHOICE OF THE APPROPRIATE PATHWAY
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DOI:
10.1016/0012-1606(80)90351-6
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发表时间:
1980-01-01
影响因子:
2.7
通讯作者:
GHYSEN, A
GHYSEN, A
中科院分区:
生物学3区
文献类型:
--
作者:
GHYSEN, A

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确定的胸部感觉神经元回填过氧化物酶在野生型果蝇,在突变体无翅contrabithorax,盾形,双胸postbithorax和毛翼,并在中枢神经系统中的投影进行了分析。感觉神经元分为4类,因为它们沿着4条一般通路中的沿着1条投射。在特定的发育隔室中,所有位于特定类型感觉结构之下的神经元都特定地遵循这些通路之一。在4个类别中的至少2个类别内,投射的细节可以根据神经元所源自的表皮的特定区域以及根据沿前后轴的沿着位置而变化。一般路径的选择可能取决于神经元的发育历史,而每个投射的细节取决于其位置。
Identified thoracic sensory neurons were backfilled with peroxidase in wild-type Drosophila, and in the mutants wingless contrabithorax, scute, bithorax postbithorax and hairy-wing, and their projection in the CNS was analyzed. The sensory neurons were divided into 4 classes as they project along 1 of 4 general pathways. All neurons which underly a given type of sensory structure in a given developmental compartment followed specifically one of these pathways. Within at least 2 of the 4 classes, the details of the projection can vary according to the particular region of the epidermis from which the neuron derives, and according to the position along the anteroposterior axis. The choice of a general pathway may depend on the developmental history of the neuron, while the detail of each projection depends on its position.