Fungicidal activity of β-thujaplicin analogues

Fungicidal activity of β-thujaplicin analogues
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DOI:
10.1002/ps.379
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发表时间:
2001-09-01
影响因子:
4.1
通讯作者:
Gérardin, P
Gérardin, P
中科院分区:
农林科学1区
文献类型:
--
作者:
Baya, M;Soulounganga, P;Gérardin, P

文献摘要

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研究了β-崖柏素(一种天然产物,负责几种柏科树木心材的耐久性)的类似物在体外对参与木材生物降解的不同白色和褐腐真菌(杂色革盖菌(Coriolus versicolor)、黄孢原毛革菌(Carrierochaete chrysosporium)、胎盘革菌(Carrierplacenta)和密粘褶菌(Gloephyllum trabeum))的生长的杀真菌活性。研究表明,2-羟基环庚-2,4,6-三烯酮(托酚酮),根据文献方法容易地制备,当与β-崖柏菌素、阿扎康唑、戊唑醇和铜喹啉相比时,具有令人感兴趣的杀真菌活性,这表明该化合物应进一步作为用于木材防腐的潜在杀生物剂进行研究。(C)2001年,化学工业协会。
The fungicidal activity of analogues of beta -thujaplicin, a natural product responsible for the durability of heartwood of several cupressaceous trees, was investigated in vitro on the growth of different white and brown rot fungi involved in wood biodegradation, Coriolus versicolor, Phanerochaete chrysosporium, Poria placenta and Gloephyllum trabeum. The study shows that 2-hydroxycyclohepta-2,4,6-trienone (tropolone), easily prepared according to a literature procedure, possesses interesting fungicidal activity when compared to beta -thujaplicin, azaconazole, tebuconazole and copper oxine, which suggests this compound should be examined further as a potential biocide for wood preservation. (C) 2001 Society of Chemical Industry.