TROPHIC EFFECTS OF PERIPHERAL ADRENERGIC-NERVES ON VASCULAR STRUCTURE

TROPHIC EFFECTS OF PERIPHERAL ADRENERGIC-NERVES ON VASCULAR STRUCTURE
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DOI:
10.1161/01.hyp.6.6_pt_2.iii19
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发表时间:
1984-01-01
期刊:
影响因子:
8.3
通讯作者:
BEVAN, RD
BEVAN, RD
中科院分区:
医学1区
文献类型:
--
作者:
BEVAN, RD

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在大鼠和兔子中,交感神经对血管模式和结构的营养作用的证据已经被审查。已经通过去神经支配和神经支配技术对来自不同区域的不同大小的血管确定了效果。去神经后,所有年龄段的人都会出现对收缩剂的非特异性敏感性增加。相反,在生长过程中主要观察到交感神经营养对肌肉质量、细胞外动脉成分和微脉管系统中血管数量的影响。这种作用的机制尚不清楚,但兔子的中央耳动脉与神经冲动有关。
In the rat and rabbit, evidence for a trophic action of sympathetic nerves on vascular pattern and structure has been reviewed. Effects have been identified by denervation and reinnervation techniques in blood vessels of different size from different regions. Following denervation, increased nonspecific sensitivity to constrictor agents occurs at all ages. In contrast, sympathetic trophic effects on muscle mass, extracellular artery components, and vessel number in the microvasculature were observed predominantly during growth. The mechanism of this action is not known, but the central ear artery in the rabbit was associated with nerve impulses.