Effect of dietary soybean protein level on the plasma homocysteine concentration in rats
Effect of dietary soybean protein level on the plasma homocysteine concentration in rats
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DOI：
10.1271/bbb.70797
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发表时间：
2008-06-01
影响因子：
1.6
通讯作者：
Sugiyama, Kimio
中科院分区：
文献类型：
--
作者：
Okawa, Hiroshi;Morita, Tatsuya;Sugiyama, Kimio
以大豆分离蛋白（SPI）为蛋白质来源时，血浆同型半胱氨酸浓度与膳食蛋白质水平或蛋白质摄入量呈负相关。肝脏胱硫醚P-合成酶活性增加，响应于饮食SPI水平。结果提示，高蛋白饮食可能是降低血浆同型半胱氨酸浓度的有效手段，其机制可能是通过增强同型半胱氨酸代谢活性。
There was an inverse correlation between the plasma homocysteine concentration and dietary protein level or protein intake when a soybean protein isolate (SPI) was used as a protein source for rats. The hepatic cystathionine P-synthase activity increased in response to the dietary SPI level. The results suggest that a high-protein diet might be an effective means to lower the plasma homocysteine concentration, probably through enhancement of the homocysteine-metabolizing activity.