Phasic spiking in vasopressin neurons: How and Why.

Phasic spiking in vasopressin neurons: How and Why.
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加压素神经元的阶段性尖峰:如何和为什么。

DOI:
10.1111/jne.13042
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发表时间:
2021
影响因子:
3.2
通讯作者:
MacGregor DJ
MacGregor DJ
中科院分区:
医学3区
文献类型:
--
作者:
MacGregor DJ

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简单的标题可能是一个几乎复古听起来脾气暴躁的反驳,但它激发了各种各样的旅程,和一些沿着的方式,我希望你不会遇到过。下丘脑视上核和室旁核大细胞加压素神经元独特的时相性尖峰模式的探索。一种主要是生命必需的神经元群体,其向肾脏发出信号以响应于编码血浆体积和渗透压的信号来调节水分损失,以及调节血压,并且可能是代谢和社会行为。一个没有任何明确数学的建模者的观点。
The plain title might have been an almost retro sounding grumpy retort, but it has inspired a journey of sorts, and something along the way I hope you won’t have come across before. An opinionated exploration of the distinctive phasic spiking patterns of magnocellular vasopressin neurons of the supraoptic and paraventricular nuclei of the hypothalamus. A mostly life essential population of neurons that signal the kidneys to regulate water loss in response to signals that encode plasma volume and osmotic pressure, as well as regulating blood pressure, and possibly metabolism and social behaviour. The viewpoint of a modeller shorn of any explicit maths.