The Gulf oil spill, miscarriage, and infertility: the GROWH study.
The Gulf oil spill, miscarriage, and infertility: the GROWH study.
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DOI：
10.1007/s00420-017-1257-4
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发表时间：
2018-01
影响因子：
3
通讯作者：
Buekens P
中科院分区：
文献类型：
--
作者：
Harville EW;Shankar A;Zilversmit L;Buekens P
旨在检查报告的海湾漏油事件（2010 年）暴露是否与报告的流产或不孕症有关。通过产前诊所和妇女、婴儿和儿童 (WIC) 诊所以及社区活动招募的 1524 名 18-45 岁女性接受了采访，了解她们的漏油经历和生育史。 1,434 名妇女获得了至少一次怀孕结果的信息，633 名妇女获得了泄漏之前和之后怀孕的信息。使用广义估计方程来研究与石油接触与泄漏造成的经济和社会后果之间的关系，包括推迟怀孕、流产和不孕（怀孕时间 > 12 个月或报告的生育问题），并对年龄、种族、体重指数、吸烟和社会经济状况进行调整。比较了漏油事件前后怀孕的结果。 77 名 (5.1%) 女性报告因漏油事件而推迟怀孕，这种情况在那些经常接触石油或总体高度暴露的女性中更为常见（aOR 2.92，95% CI 1.31-6.51）。发现任何接触石油泄漏的情况都会增加流产的风险（aOR，1.54，95% CI 1.17-2.02）。当数据仅限于怀孕前后的女性时，生育问题在总体上暴露程度最高的女性中更为常见（aOR 1.88、1.19-2.95）。然而，石油泄漏暴露没有任何特定方面与结果密切相关，并且对石油泄漏之前怀孕的影响几乎同样强烈。漏油事件似乎影响了生殖决策。没有强有力的证据表明接触石油泄漏与流产或不孕有关。
To examine whether reported exposure to the Gulf oil spill (2010) was related to reproductive reported miscarriage or infertility. 1524 women aged 18–45 recruited through prenatal and Women, Infant, and Children (WIC) clinics, and community events were interviewed about their experience of the oil spill and reproductive history. 1434 women had information on outcomes of at least one pregnancy, and 633 on a pregnancy both before and after the spill. Generalized estimating equations were used to examine the relationship between contact with oil and economic and social consequences of the spill with postponement of pregnancy, miscarriage, and infertility (time to pregnancy >12 months or reported fertility issues), with adjustment for age, race, BMI, smoking, and socioeconomic status. Results were compared for pregnancies occurring prior to and after the oil spill. 77 (5.1%) women reported postponing pregnancy due to the oil spill, which was more common in those with high contact with oil or overall high exposure (aOR 2.92, 95% CI 1.31–6.51). An increased risk of miscarriage was found with any exposure to the oil spill (aOR, 1.54, 95% CI 1.17–2.02). Fertility issues were more common in the overall most highly exposed women (aOR 1.88, 1.19–2.95), when the data were limited to those with pregnancies before and after. However, no particular aspect of oil spill exposure was strongly associated with the outcomes, and effects were almost as strong for pregnancies prior to the oil spill. The oil spill appears to have affected reproductive decision-making. The evidence is not strong that exposure to the oil spill was associated with miscarriage or infertility.
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DOI：
10.1034/j.1600-0412.2000.079006471.x
发表时间：
2000-06-01
影响因子：
4.3
作者：
Kristensen, P;Irgens, LM
通讯作者：
Irgens, LM
影响因子：
2.7
作者：
Osofsky, Howard J.;Osofsky, Joy D.;Hansel, Tonya C.
通讯作者：
Hansel, Tonya C.
影响因子：
6.3
作者：
JOFFE, M;VILLARD, L;VESSEY, M
通讯作者：
VESSEY, M
影响因子：
0.8
作者：
Fujimori, Keiya;Kyozuka, Hyo;Abe, Masafumi
通讯作者：
Abe, Masafumi
DOI：
10.1097/ede.0b013e31818ef47e
发表时间：
2009-01
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Cooney MA;Buck Louis GM;Sundaram R;McGuiness BM;Lynch CD
通讯作者：
Lynch CD