Dynamics of conduction blocks in a model of paced cardiac tissue.
Dynamics of conduction blocks in a model of paced cardiac tissue.
复制标题
起搏心脏组织模型中传导阻滞的动力学。
DOI：
10.1103/physreve.71.051911
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Rappel,Wouter-Jan
中科院分区：
文献类型：
--
作者：
Henry,Herve;Rappel,Wouter-Jan
我们使用详细的电生理学模型数值研究传导阻滞的动力学。我们发现，这种动态关键取决于起搏区域的大小。小的起搏区域导致静止传导阻滞，而较大的起搏区域可导致周期性地朝向起搏区域行进的传导阻滞。我们表明，这种大小依赖性的动力学可以导致一种新的产氢机制。此外，我们表明，基本的现象可以捕捉到一个更简单的耦合映射模型。
We study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region. Small pacing regions lead to stationary conduction blocks while larger pacing regions can lead to conduction blocks that travel periodically towards the pacing region. We show that this size-dependence dynamics can lead to a novel arrhythmogenic mechanism. Furthermore, we show that the essential phenomena can be captured in a much simpler coupled-map model.