Sex and strain-related differences in the peripheral blood cell values of inbred mouse strains

Sex and strain-related differences in the peripheral blood cell values of inbred mouse strains
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DOI:
10.1007/s00335-002-2160-0
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发表时间:
2003-01-01
期刊:
影响因子:
2.5
通讯作者:
Justice, MJ
Justice, MJ
中科院分区:
生物学4区
文献类型:
--
作者:
Kile, BT;Mason-Garrison, CL;Justice, MJ

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文章引用了一项关于近交系小鼠外周血细胞值的性别和品系相关差异的研究。随着小鼠基因组测序的接近完成,实验生物学正在进入一个新时代。小鼠是用于确定哺乳动物基因功能和人类疾病模型的主要实验生物。除了在大小、世代时间和进化上与人类接近等方面的优势外,近交系的可用性使小鼠非常适合遗传研究。
The article cites a study on sex and strain-related differences in the peripheral blood cell values of inbred mouse strains. With the sequencing of the mouse genome nearing completion, experimental biology is entering a new era. The mouse is the primary experimental organism used to define mammalian gene function and model human disease. Besides the advantages it offers with regard to size, generation time, and evolutionary proximity to humans, the availability of inbred strains makes the mouse highly amenable to genetic investigation.