TOPOGRAPHIC ORGANIZATION OF SUBCORTICAL PROJECTIONS TO THE ANTERIOR THALAMIC NUCLEI IN THE RAT
TOPOGRAPHIC ORGANIZATION OF SUBCORTICAL PROJECTIONS TO THE ANTERIOR THALAMIC NUCLEI IN THE RAT
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DOI：
10.1002/cne.903230110
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发表时间：
1992-09-01
影响因子：
2.5
通讯作者：
SHIBATA, H
中科院分区：
文献类型：
--
作者：
SHIBATA, H
用辣根过氧化物酶标记的麦胚凝集素逆行和顺行运输方法，研究了大鼠皮层下向丘脑前核的投射，特别是乳头体核的投射.乳头体内侧核（MM）主要向同侧整个丘脑前核投射，而外侧乳头体核向两侧投射到丘脑前核的前背核（AD）。MM和丘脑前核之间的地形关系被确认。内侧核内侧部的背侧区投射到前内侧核（interanteromedial nucleus，IAM），而腹侧区投射到前内侧核（anteromedial nucleus，AM）的吻侧部。内侧部的背侧和腹侧区域分别在尾侧和吻侧水平投射到AM的背内侧部。外侧部的背内侧区投射到腹侧AM。外侧部的腹外侧区投射到前腹侧核（AV）的腹侧部分，其投射方式为吻侧细胞向吻侧投射，尾侧细胞向尾侧投射。基底部主要投射到同侧AV背外侧和双侧AD。后部的吻外侧区投射到AV外侧，而后部的内侧和尾部区投射到AV背内侧。发现丘脑网状核的吻背侧部投射到前核;位于该部分的吻侧细胞投射到IAM和AM，而位于尾背侧的细胞投射到AV和AD。背外侧被盖核主要投射到AV的同侧，特别是其背外侧部分。本研究表明，皮质下结构的分区连接到丘脑前核的亚核，具有明确的地形安排在背腹侧和喙尾侧的尺寸。
Subcortical projections to the anterior thalamic nuclei were studied in the rat, with special reference to projections from the mammillary nuclei, by retrograde and anterograde transport of wheat germ agglutinin conjugated to horseradish peroxidase.The medial mammillary nucleus (MM) projects predominantly ipsilaterally to the entire anterior thalamic nuclei, whereas the lateral mammillary nucleus projects bilaterally to the anterodorsal nucleus (AD) of the anterior thalamic nuclei. A topographic relationship was recognized between the MM and the anterior thalamic nuclei. The dorsal region of the pars mediana of the MM projects to the interanteromedial nucleus (IAM), whereas the ventral region projects to the rostral part of the anteromedial nucleus (AM). The dorsal and the ventral regions of the pars medialis project to the dorsomedial part of the AM at its caudal and rostral levels, respectively. The dorsomedial region of the pars lateralis projects to the ventral AM. The ventrolateral region of the pars lateralis projects to the ventral part of the anteroventral nucleus (AV) in such a manner that rostral cells project rostrally and caudal cells project caudally. The pars basalis projects predominantly ipsilaterally to the dorsolateral AV and bilaterally to the AD. The rostrolateral region of the pars posterior projects to the lateral AV, whereas the medial and the caudal regions of the pars posterior project to the dorsomedial AV.The rostrodorsal part of the nucleus reticularis thalami was found to project to the anterior thalamic nuclei; cells located rostrally in this part project to the IAM and AM, whereas cells located caudodorsally project to the AV and AD. The laterodorsal tegmental nucleus projects predominantly ipsilaterally to the AV, especially to its dorsolateral part.The present study demonstrates that subdivisions of the subcortical structures are connected to the subnuclei of the anterior thalamic nuclei, with a clear-cut topography arranged in the dorsoventral and the rostrocaudal dimensions.